Table 2.

FSRs and Daily Mevalonic Acid Excretion of Subjects Consuming Diets Differing in Dietary Cholesterol

Dietary Cholesterol Level
LowMediumHighLowMediumHigh
FSRs, Pools/dMevalonic Acid Excretion, μmol/d
Hypo
 10.02760.03520.07012.0591.8831.467
 200.03260.03261.2771.6481.652
 30.10710.08620.05982.1852.6252.877
 40.09450.10080.02112.3831.721.449
 50.09030.06520.05122.2892.1652.18
 60.09060.03670.04122.032.092.04
 70.08750.05280.06194.052.011.94
Mean±SEM0.0711±0.01530.0585±0.01010.0483±0.00702.325±0.1392.021±0.1231.944±0.192
Normo
 80.09490.10460.13642.5232.681.695
 90.05960.05350.05454.3443.0151.985
 100.10580.09690.07641.3851.4391.260
 1100.04880.09641.912.092.499
 120.12260.05390.10652.7642.0652.016
 130.06160.06510.0285NA1.5121.007
 140.08860.06810.07931.9341.7761.889
 150.09630.08990.02512.3812.192.33
 160.06850.04560.03673.9683.4833.08
 170.0990.05270.04752.1541.2750.896
 180.07120.07680.05181.5311.2371.168
 190.04550.03530.02192.345NA2.12
Mean±SEM0.0756±0.00950.0659±0.00600.0634±0.01042.476±0.2802.069±0.2221.829±0.189
Hyper
 20NA0.0156NA1.9102.1181.054
 210.02970.01330.07731.6281.2530.59
 220.05290.0680.04441.821.8301.509
 230.05960.04810.03541.2440.7841.092
 240.1150.06230.06221.51.1181.333
 250.07210.07550.09462.0672.5422.327
 260.07820.072102.0784.1091.864
 270.02620.01280.03792.4782.0951.39
 280.06280.03460.04551.7422.1991.962
 290.04570.06610.05022.542.3452.84
 300.08550.08980.03321.6791.3781.347
Mean±SEM0.0628±0.00840.0507±0.00820.0481±0.00821.881±0.1181.979±0.2721.573±0.191
  • Hypo indicates hypocholesterolemic; normo, normocholesterolemic; hyper, hypercholesterolemic; and NA, not available.