Table 2. Association of APOA5 and USF1 Variants With TGs and HDL Cholesterol in Australian ADL Families (n=516)

Variable (n=516)MAF, %TGs, mmol/LHDL Cholesterol, mmol/L
1/2*1 11 22 2P1 11 22 2P
Data are presented as mean±SE. NA indicates genotype not observed; MAF, minor allele frequency.
*Data show major and minor alleles of the variant, respectively. Major allele is represented by “1” and minor allele by “2.”
†The critical P value for 5% significance is 0.005 using Bonferroni correction for 10 tests.
P value is smaller than the critical P value using Bonferroni correction.
APOA5
    rs313550612G/C2.33±0.072.82±0.213.84±0.530.00471.13±0.021.07±0.020.88±0.090.07
    rs6627997A/G2.34±0.082.83±0.205.30±2.900.0061.13±0.021.07±0.040.95±0.050.37
    rs171200358C/T2.44±0.082.50±0.17NA0.671.13±0.021.04±0.03NA0.01
    rs1075009727A/G2.21±0.082.63±0.143.15±0.270.000091.16±0.021.08±0.021.00±0.040.001
USF1
    rs1090882114C/G2.46±0.092.47±0.141.91±0.290.791.13±0.021.07±0.021.17±0.130.26
    rs207365824C/T2.36±0.092.55±0.122.92±0.550.591.12±0.021.11±0.031.08±0.070.68
    rs277427626C/G2.46±0.092.53±0.131.80±0.160.501.12±0.021.11±0.021.18±0.070.77
    rs251683941T/C2.45±0.142.63±0.111.95±0.110.0471.14±0.031.10±0.021.14±0.040.81
    rs155625915A/G2.50±0.092.31±0.112.43±0.310.221.12±0.021.12±0.031.08±0.060.43
    rs277427934G/A2.41±0.112.49±0.122.42±0.170.351.10±0.021.14±0.021.11±0.040.34