Arteriosclerosis, Thrombosis, and Vascular Biology -- Table of Contents (29 [2])

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Volume 29, Issue 2; February 1, 2009

Editorials
History of Discovery
Brief Reviews
Integrative Physiology/Experimental Medicine
Cell Biology/Signaling
Clinical and Population Studies

Key: VB = Vascular Biology AL = Atherosclerosis/Lipoproteins TH = Thrombosis

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	Editorials
	Cause or Consequence: What Does Macrophage Apoptosis Do in Atherosclerosis? Murray C.H. Clarke and Martin R. Bennett Arterioscler Thromb Vasc Biol. 2009;29:153-155; published online before print November 26 2008, doi:10.1161/ATVBAHA.108.179903 Extract \| Full Text \| PDF
	Is H₂S a Stinky Remedy for Atherosclerosis? Rui Wang Arterioscler Thromb Vasc Biol. 2009;29:156-157; published online before print November 26 2008, doi:10.1161/ATVBAHA.108.180190 Extract \| Full Text \| PDF
	History of Discovery
	Discovery of the Role of Wall Shear in Atherosclerosis C.G. Caro Arterioscler Thromb Vasc Biol. 2009;29:158-161; published online before print November 26 2008, doi:10.1161/ATVBAHA.108.166736 Abstract \| Full Text \| PDF
	Brief Reviews
	Calcific Aortic Stenosis: Lessons Learned From Experimental and Clinical Studies Nalini M. Rajamannan Arterioscler Thromb Vasc Biol. 2009;29:162-168; published online before print November 20 2008, doi:10.1161/ATVBAHA.107.156752 Abstract \| Full Text \| PDF Calcific aortic stenosis was once thought to be a degenerative process. Experimental models developed in the 21st century are providing evidence that this disease has an active cellular biology. This review will outline these models and discuss the translational clinical implications for calcific aortic stenosis to provide a foundation for future clinical trials in the field of valvular heart disease.
	Brief Report: Increased Apoptosis in Advanced Atherosclerotic Lesions of Apoe^–/– Mice Lacking Macrophage Bcl-2 Edward Thorp, Yankun Li, Liping Bao, Pin Mei Yao, George Kuriakose, James Rong, Edward A. Fisher, and Ira Tabas Arterioscler Thromb Vasc Biol. 2009;29:169-172; published online before print November 6 2008, doi:10.1161/ATVBAHA.108.176495 Abstract \| Full Text \| PDF \| Data Supplement
	Integrative Physiology/Experimental Medicine
	Role of Hydrogen Sulfide in the Development of Atherosclerotic Lesions in Apolipoprotein E Knockout Mice Yanfei Wang, Xia Zhao, Hongfang Jin, Hongling Wei, Wei Li, Dingfang Bu, Xiuying Tang, Yali Ren, Chaoshu Tang, and Junbao Du Arterioscler Thromb Vasc Biol. 2009;29:173-179; published online before print November 6 2008, doi:10.1161/ATVBAHA.108.179333 Abstract \| Full Text \| PDF \| Data Supplement
	Core2 1-6-N-Glucosaminyltransferase-I Is Crucial for the Formation of Atherosclerotic Lesions in Apolipoprotein E–Deficient Mice Huan Wang, Rong Tang, Weiyu Zhang, Karine Amirikian, Zhen Geng, Jianguo Geng, Robert P. Hebbel, Lijun Xia, Jamey D. Marth, Minoru Fukuda, Shigeki Katoh, and Yuqing Huo Arterioscler Thromb Vasc Biol. 2009;29:180-187; published online before print December 4 2008, doi:10.1161/ATVBAHA.108.170969 Abstract \| Full Text \| PDF \| Data Supplement
	Leukocyte Cathepsin S Is a Potent Regulator of Both Cell and Matrix Turnover in Advanced Atherosclerosis R. de Nooijer, I. Bot, J.H. von der Thüsen, M.A. Leeuwenburgh, H.S. Overkleeft, A.O. Kraaijeveld, R. Dorland, P.J. van Santbrink, S.H. van Heiningen, M.M. Westra, P.T. Kovanen, J.W. Jukema, E.E. van der Wall, Th.J.C. van Berkel, G.P. Shi, and E.A.L. Biessen Arterioscler Thromb Vasc Biol. 2009;29:188-194; published online before print December 18 2008, doi:10.1161/ATVBAHA.108.181578 Abstract \| Full Text \| PDF \| Data Supplement To address the role of leukocyte cathepsin-S in advanced lesion composition, we generated chimeric LDLr-/- mice deficient in leukocyte CatS by transplantation with CatS-/-xLDLr-/- or with LDLr-/- bone marrow. CatS deficiency resulted in considerably altered plaque morphology, with smaller necrotic cores, reduced apoptosis, and decreased SMC content and collagen deposition.
	Soluble N-Cadherin Overexpression Reduces Features of Atherosclerotic Plaque Instability Cressida A. Lyon, Jason L. Johnson, Helen Williams, Graciela B. Sala-Newby, and Sarah J. George Arterioscler Thromb Vasc Biol. 2009;29:195-201; published online before print November 13 2008, doi:10.1161/ATVBAHA.108.178087 Abstract \| Full Text \| PDF \| Data Supplement
	Cell Biology/Signaling
	GIT1 Mediates VEGF-Induced Podosome Formation in Endothelial Cells: Critical Role for PLC ${gamma}$ Jing Wang, Yoji Taba, Jinjiang Pang, Guoyong Yin, Chen Yan, and Bradford C. Berk Arterioscler Thromb Vasc Biol. 2009;29:202-208; published online before print November 20 2008, doi:10.1161/ATVBAHA.108.174391 Abstract \| Full Text \| PDF
	Early Growth Response-1 Regulates Angiopoietin-1-Induced Endothelial Cell Proliferation, Migration, and Differentiation Nelly A. Abdel-Malak, Mahroo Mofarrahi, Dominique Mayaki, Levon M. Khachigian, and Sabah N.A. Hussain Arterioscler Thromb Vasc Biol. 2009;29:209-216; published online before print December 26 2008, doi:10.1161/ATVBAHA.108.181073 Abstract \| Full Text \| PDF \| Data Supplement
	Endothelial Nitric Oxide Synthase Inhibits G_12/13 and Rho-Kinase Activated by the Angiotensin II Type-1 Receptor: Implication in Vascular Migration Hiroyuki Suzuki, Keita Kimura, Heigoro Shirai, Kunie Eguchi, Sadaharu Higuchi, Akinari Hinoki, Kazuhiro Ishimaru, Eugen Brailoiu, Danny N. Dhanasekaran, Laura N. Stemmle, Timothy A. Fields, Gerald D. Frank, Michael V. Autieri, and Satoru Eguchi Arterioscler Thromb Vasc Biol. 2009;29:217-224; published online before print December 18 2008, doi:10.1161/ATVBAHA.108.181024 Abstract \| Full Text \| PDF \| Data Supplement The effect of endothelial nitric oxide synthase (eNOS) gene transfer on signal cross-talk with Rho and Rho-kinase activated by angiotensin II was investigated. We found that eNOS inhibited the Rho/ROCK pathway activated by angiotensin II via inhibition of G12/13. Because this leads to inhibition of vascular cell migration induced by angiotensin II, our findings reveal a novel signal cross-talk explaining vascular protection via nitric oxide.
	Molecular Mechanisms of Collagen Isotype-Specific Modulation of Smooth Muscle Cell Phenotype A. Wayne Orr, Monica Y. Lee, Julia A. Lemmon, Arif Yurdagul, Jr, Maria F. Gomez, Pamela D. Schoppee Bortz, and Brian R. Wamhoff Arterioscler Thromb Vasc Biol. 2009;29:225-231; published online before print November 20 2008, doi:10.1161/ATVBAHA.108.178749 Abstract \| Full Text \| PDF \| Data Supplement
	mTOR Regulates Vascular Smooth Muscle Cell Differentiation From Human Bone Marrow–Derived Mesenchymal Progenitors Björn Hegner, Maria Lange, Angelika Kusch, Kirill Essin, Orhan Sezer, Eckhard Schulze-Lohoff, Friedrich C. Luft, Maik Gollasch, and Duska Dragun Arterioscler Thromb Vasc Biol. 2009;29:232-238; published online before print December 12 2008, doi:10.1161/ATVBAHA.108.179457 Abstract \| Full Text \| PDF \| Data Supplement
	Nox4 Acts as a Switch Between Differentiation and Proliferation in Preadipocytes Katrin Schröder, Katalin Wandzioch, Ina Helmcke, and Ralf P. Brandes Arterioscler Thromb Vasc Biol. 2009;29:239-245; published online before print December 4 2008, doi:10.1161/ATVBAHA.108.174219 Abstract \| Full Text \| PDF \| Data Supplement
	Efficacy of Simvastatin Treatment of Valvular Interstitial Cells Varies With the Extracellular Environment Elyssa L. Monzack, Xiaoxiao Gu, and Kristyn S. Masters Arterioscler Thromb Vasc Biol. 2009;29:246-253; published online before print November 20 2008, doi:10.1161/ATVBAHA.108.179218 Abstract \| Full Text \| PDF \| Data Supplement
	Altered Shear Stress Stimulates Upregulation of Endothelial VCAM-1 and ICAM-1 in a BMP-4– and TGF-β1–Dependent Pathway Philippe Sucosky, Kartik Balachandran, Adnan Elhammali, Hanjoong Jo, and Ajit P. Yoganathan Arterioscler Thromb Vasc Biol. 2009;29:254-260; published online before print November 20 2008, doi:10.1161/ATVBAHA.108.176347 Abstract \| Full Text \| PDF \| Data Supplement
	Clinical and Population Studies
	HDL Remodeling During the Acute Phase Response Anisa Jahangiri, Maria C. de Beer, Victoria Noffsinger, Lisa R. Tannock, Chandrashekar Ramaiah, Nancy R. Webb, Deneys R. van der Westhuyzen, and Frederick C. de Beer Arterioscler Thromb Vasc Biol. 2009;29:261-267; published online before print November 13 2008, doi:10.1161/ATVBAHA.108.178681 Abstract \| Full Text \| PDF \| Data Supplement
	Torcetrapib Differentially Modulates the Biological Activities of HDL2 and HDL3 Particles in the Reverse Cholesterol Transport Pathway Giovanna Catalano, Zélie Julia, Eric Frisdal, Benoit Vedie, Natalie Fournier, Wilfried Le Goff, M. John Chapman, and Maryse Guerin Arterioscler Thromb Vasc Biol. 2009;29:268-275; published online before print November 26 2008, doi:10.1161/ATVBAHA.108.179416 Abstract \| Full Text \| PDF \| Data Supplement

Spotlight

TOC Spotlight File

Volume 29, Issue 2; February 1, 2009

Key: VB = Vascular Biology AL = Atherosclerosis/Lipoproteins TH = Thrombosis

Editorials

Cause or Consequence: What Does Macrophage Apoptosis Do in Atherosclerosis?

Is H2S a Stinky Remedy for Atherosclerosis?

History of Discovery

Discovery of the Role of Wall Shear in Atherosclerosis

Brief Reviews

Calcific Aortic Stenosis: Lessons Learned From Experimental and Clinical Studies

Brief Report: Increased Apoptosis in Advanced Atherosclerotic Lesions of Apoe–/– Mice Lacking Macrophage Bcl-2

Integrative Physiology/Experimental Medicine

Role of Hydrogen Sulfide in the Development of Atherosclerotic Lesions in Apolipoprotein E Knockout Mice

Core2 1-6-N-Glucosaminyltransferase-I Is Crucial for the Formation of Atherosclerotic Lesions in Apolipoprotein E–Deficient Mice

Leukocyte Cathepsin S Is a Potent Regulator of Both Cell and Matrix Turnover in Advanced Atherosclerosis

Soluble N-Cadherin Overexpression Reduces Features of Atherosclerotic Plaque Instability

Cell Biology/Signaling

GIT1 Mediates VEGF-Induced Podosome Formation in Endothelial Cells: Critical Role for PLC

Early Growth Response-1 Regulates Angiopoietin-1-Induced Endothelial Cell Proliferation, Migration, and Differentiation

Endothelial Nitric Oxide Synthase Inhibits G12/13 and Rho-Kinase Activated by the Angiotensin II Type-1 Receptor: Implication in Vascular Migration

Molecular Mechanisms of Collagen Isotype-Specific Modulation of Smooth Muscle Cell Phenotype

mTOR Regulates Vascular Smooth Muscle Cell Differentiation From Human Bone Marrow–Derived Mesenchymal Progenitors

Nox4 Acts as a Switch Between Differentiation and Proliferation in Preadipocytes

Efficacy of Simvastatin Treatment of Valvular Interstitial Cells Varies With the Extracellular Environment

Altered Shear Stress Stimulates Upregulation of Endothelial VCAM-1 and ICAM-1 in a BMP-4– and TGF-β1–Dependent Pathway

Clinical and Population Studies

HDL Remodeling During the Acute Phase Response

Torcetrapib Differentially Modulates the Biological Activities of HDL2 and HDL3 Particles in the Reverse Cholesterol Transport Pathway

Spotlight

Is H₂S a Stinky Remedy for Atherosclerosis?

Brief Report: Increased Apoptosis in Advanced Atherosclerotic Lesions of Apoe^–/– Mice Lacking Macrophage Bcl-2

GIT1 Mediates VEGF-Induced Podosome Formation in Endothelial Cells: Critical Role for PLC ${gamma}$

Endothelial Nitric Oxide Synthase Inhibits G_12/13 and Rho-Kinase Activated by the Angiotensin II Type-1 Receptor: Implication in Vascular Migration