On the cover: Endothelial cell staining of perfused rat renal arterioles demonstrating colocalization of phosphoMYPT1 with cortical F-actin in control vessels (arrow heads) and enhanced MYPT1 phosphorylation associated with central F-actin filaments after exposure to thrombin. Outlines of individual ECs are presented in the lower row. Arterioscler Thromb Vasc Biol. 2007;27:2332–2339.