- Manuscript must be formatted in accordance with the Instructions to Authors.
- Manuscripts cannot contain previously published data or be under consideration for publication elsewhere.
- All authors should be aware of the requirements of completing the electronic author responsibility forms and copyright transfer agreement. However, please note that the electronic author forms will only be requested for completion at the time of revision submission or when the manuscript is accepted. Electronic author forms are not required during first submission or resubmission of previously rejected manuscripts.
- All actual and perceived conflicts of interests must be stated
Wolters Kluwer Author Services
If you need help preparing a manuscript for submission, our publisher, Wolters Kluwer, in partnership with Editage, offers a unique range of editorial services for a fee, including:
- Premium Editing: Intensive language and structural editing of academic papers to improve the clarity and impact of your manuscript.
- Advanced Editing: A complete language, grammar, and terminology check to give you a publication-ready manuscript.
- Translation with Editing: Write your paper in your native language and Wolters Kluwer Author Services will translate it into English, as well as edit it to ensure that it meets international publication standards.
- Plagiarism Check: Helps ensure that your manuscript contains no instances of unintentional plagiarism.
- Artwork Preparation: Save precious time and effort by ensuring that your artwork is viewed favorably by the journal without you having to incur the additional cost of purchasing special graphics software.
For more information regarding Wolters Kluwer Author Services and to receive a quote for your manuscript, please visit wkauthorservices.editage.com. Please note that use of Wolters Kluwer Author Services does not in any way imply a guarantee, or even a likelihood, of acceptance of your manuscript in ATVB.
- Single spaced, preferable using Arial font with no less than 11 point
- 2.5 cm margins with left justification
- The order of the manuscript should be: title page, abstract, introduction, material and methods, results, discussion, acknowledgments, sources of funding, disclosures, references, highlights, tables
- Figure legends should be placed on the same page as the Figure to facilitate the review process.
- Pagination is required
- SI units are required
- Left justification is strongly preferred
- Full title (150 character limit)
- Authors names and affiliations. Equal contributions to first and senior authorship are acceptable
- Running title (50 character limit)
- Corresponding authors contact information including address, e-mail, and telephone number
- Subject codes selected from the following list: atvb.ahajournals.org/content/subject-codes
- Word count
- Total number of figures and tables
- TOC category - basic, translational, or clinical and population studies
- TOC subcategory - Arteriosclerosis, Thrombosis, and Vascular Biology
- Use the following headings - Objective, Approach and Results, Conclusions
- Length is limited to 250 words
- Do not include references
- Minimize the use of abbreviation
- The intent of the graphic abstract is to provide readers with a succinct summary of the study in a form that facilitates its dissemination in presentations.
- The graphic abstract can be submitted at any time, but is an absolute requirement for revision submission.
- The graphic abstract should conform to the following format:
- A single figure panel
- Size: the submitted image should be no more than a 15 cm square (15 cm x 15 cm)
- Font: prefer a san serif font that is no less than 12 point.
- Placement in manuscript should be immediately after the written abstract
- Emphasize the new findings in the paper
- Do not include data items; all content should be graphical
- Please upload as a supplemental file in PDF file format.
- Should appear in the manuscript after the abstract
- All non standard abbreviations should be listed
- All abbreviations and acronyms should still be expanded upon first use.
- Abbreviations should only be used on words or phrases that are repeated more than 5 times in the article.
Materials and Methods **(Changes Updated January 2018 - please read, follow carefully and amend in your submission as needed)**
- Please ensure that your manuscript adheres to the AHA Journals; implementation of the Transparency and Openness Promotion (TOP) Guidelines (available online at http://www.ahajournals.org/content/TOP-guidelines
- Materials and Methods text, along with corresponding references, will be listed within the manuscript text, after the Introduction and before the Results sections. Materials and Methods text will no longer be listed in Supplemental Material and should be listed in full within the manuscript text.
- You may list some Materials and Methods text in Supplemental Material, but please note that all references must first be mentioned in the manuscript text before mention in the Supplemental Materials alone. So any references in the Supplemental Material must first be mentioned in the manuscript text.
- The manuscript must include sufficient detail to permit others to replicate the studies. Therefore, the Materials and Methods section must contain sufficient details. This is to be combined with an online supplement that contains “Major Resource Tables”, and can also contain any other information to facilitate replication. A Template “Major Resources Table” is available by clicking here. All references related to the description of methods must be within the manuscript text. Citation of papers that have already provided extensive experimental details is permissible but the cited reference must satisfy the criterion of providing sufficient detail to permit replications. Methods should cite any statement(s) that are relevant to the execution of the experimental design and technique.
- This section must include a detailed description of the statistical tests used to support the stated conclusions.
- Anything needing listing in the “Major Resource Table” can be listed in the manuscript text, but must be listed in the “Major Resources Table” and not just the text.
- The “Major Resources Table” should be referenced in the text as "please see the Major Resources Table in the Supplemental Material. The “Major Resources Table” should be uploaded as a Supplemental File in PDF format with the file title “Major Resources Table."
- The "Major Resources Table" should be uploaded as an individual Supplemental File in PDF format with the file title “Major Resources Table."
- Experimental animals: State whether the animal study was approved by The Institutional Animal Care and Use Committee. State the species, strain, sex, number used, and pertinent descriptive characteristics. When describing surgical procedures, identify the preanesthetic and anesthetic agents used and the amounts, concentrations, routes, and frequency of administration of each. Paralytic agents are not considered acceptable substitutes for anesthetics. For other invasive procedures on animals, report the analgesic or tranquilizing drug used. If none were used, provide justification for exclusion.
- Human studies: Indicate that the study was approved by an institutional review board along with the name of the IRB, and that the participants gave written informed consent (or that no informed consent was required).
- The Acknowledgments section must be formatted into the three sections mentioned below (If there is nothing to list within a section, please still list the section with "none"):
- a) Acknowledgments: This area is to acknowledge contributions to the manuscripts. All individuals included in this section must provide written acknowledgment of their agreement to be included. All persons acknowledged must have seen and approved mention of their names in the article, as readers may infer their endorsement of data and conclusions.
- b) Sources of Funding: State funding that supported the studies.
- c) Disclosures: All actual or potential perceived conflicts of interests should be stated.
- References should be formatted as per journal standards.
- List all authors, except for articles containing more than 15+ authors, abbrreviate to the first three authors and then use "et.al."
- Cite references in numerical order.
- Please note that all references must first be mentioned in the manuscript text before mention in the Supplemental Materials alone. So any references in the Supplemental Material must first be mentioned in the manuscript text.
- Citation of unpublished work and personal communications is not permissible.
- Citations of submitted or in press work required the manuscript to be included in the submission process.
- Abstracts may be cited only if they are the sole source and must be identified in the reference as "Abstract."
- References are included in the 7,500 word limit.
- Examples of AMA reference listings:
- Example of journal reference:
Patel VA, Zhang Q-J, Siddle K, Soos MA, Goddard M, Weissberg PL, Bennett MR. Defect in insulin-like growth factor-1 survival mechanism in atherosclerotic plaque-derived vascular smooth muscle cells is mediated by reduced surface binding and signaling. Arterioscler Thromb Vasc Biol. 2012;32:2043-2044.
- Example of book reference:
Gourdie RG, Litchenberg WH, Eisenberg LM. Gap junctions in heart development. In: DeMello WC, Janse MJ, eds. Heart Cell Communication in Health and Disease. Boston, Mass: Kluwer; 1998:19–44.
- Example of published abstract reference:
ISIS Collaborative Group. ISIS-4: randomised study of oral isosorbide mononitrate in over 50,000 patients with suspected acute myocardial infarction [abstract 2112]. Circulation. 1993;88(suppl):I-394.
- Example of web site reference:
International Society for Infectious Diseases. ProMED-mail Web site. http://www.promedmail.org/. Accessed February 14, 2014.
- Example of patent references:
- Furukawa Y, Kishimoto S, Nishikawa K. Hypotensive imidazole derivatives. US Patent 4,340,598. July 5, 1982.
- Carini DJ, Wong PC, Duncia JV. Angiotensin II receptor blocking imidazoles and combinations thereof with diuretics and NSAID. European Patent Application 0324377 issued to EI du Pont de Nemours & Co, Inc, Wilmington, Del, 1989.
- Example of journal reference:
- 3-5 bullet points that summarize the major findings of the study.
- Place after the References.
- Tables should be provided with a heading and a legend that permits evaluation of the data
- Include table(s) in the main manuscript document as text, not as an image. Table(s) are included in the word limit.
- Number tables using Arabic numerals, and supply a brief, informative title for each table.
- Table text must be consistent in size and style with main manuscript text.
- Supply brief column headings.
- Indicate footnotes in this order: *, †, ‡, §, ||, #, **
- Use only horizontal borders above and below the column headings and at the bottom of the table. Use extra space to delineate rows and columns.
- Abbreviations/symbols used in a table but not already defined in the main text must be defined in the table or table legend.
- Tables should be cell-based (ie, constructed using Microsoft Word tables or Excel). Do not use tabs or hard returns. Do not supply tables as graphics.
- Tables should be used to present comparisons of large amounts of data at a glance. Tables with only 1 or 2 rows should be incorporated into the text.
- Tables should be as compact as possible. Avoid unnecessary rows and columns.
- Units of measure should be in the heading row or stub column rather than the body of the table whenever possible.
- Follow AMA 9th edition for footnote styles.
- Each figure for review and its corresponding legend should be presented together on its own page within the manuscript PDF.
- Acceptable electronic figure file formats for publication: TIFF, Photoshop, PDF, PowerPoint.
- Color figures should be submitted in RGB mode.
- Color figures and line drawings must be at least 600-dpi resolution. Grayscale and black/white figures must be at least 300-dpi resolution.
- Combination color, grayscale and line art must be 600 dpi or higher.
- The use of digital media for image acquisition and processing introduces the potential for inadvertent distortion of data. To prevent such distortion, data should neither be added to, nor removed from, an image by digital manipulation. Figures assembled from multiple images must indicate the separation of the parts by lines.
- Linear adjustment of contrast, brightness or color must be applied equally to all parts of an image.
- Authors must be prepared to submit the original, unaltered files from which the submitted figures were derived, if requested by the editorial office.
- Graphics downloaded from the Web are not acceptable for print. Web graphics, usually in GIF or JPEG format, have a resolution of only 72 dpi, which does not meet the standard for peer review nor publication.
- Authors are responsible for the cost of printing color figures (see “Costs to Authors”).
- Figure parts should be clearly labeled. Letters and labels must be uniform in size and style within each figure and, when possible, between figures. The font size must be 11 point or higher. Labels for panels should be uppercase letters (A, B, C, etc) in boldface Arial or Helvetica.
- Limit white space between figure panels and within each panel.
- Use the same font (typeface) throughout the figure. Sans serif fonts, such as Arial and Helvetica, work best.
- Use the largest font size possible without distorting the figure. Text should be no smaller than 6 points.
- Whenever possible, all text within a figure should be the same size. If this is not possible, the font size should vary by no more than 2 points.
- Supply a scale bar with photomicrographs.
- Symbols and abbreviations must be defined in the figure or its legend.
- Avoid headings on the figure. Heading information should appear in the figure legend.
- Figure legends are included in the word limit.
- If the figure is reprinted/adapted from another source, please provide a permission letter and include the source in the legend. If no language is provided in the permission letter, use the following sample: Reprinted from Butler et al, with permissions from Smith Publishing. Copyright 2005, American Society of Medical Research.
- NEW FEATURE: View guidelines and examples (PDF) for presenting compact and legible figures and tables. View for additional image preparation (PDF).
- The Online Supplement undergoes peer review and must be submitted simultaneiously with the original manuscript submission
- The Online Supplement must contain its own independent reference section with references numbered sequentially, beginning with reference 1, even if some of these references duplicate those in the print version.
- With the exception of video files and large datasets in Excel file format, authors must compile all Online Supplement materials into one (1) PDF file. The first page of this PDF should include the heading, "SUPPLEMENTAL MATERIAL." This PDF should include the following supplemental material: Supplemental Figures and Figure Legends, Supplemental Tables, Supplemental References, and Legends for the Video files. Please upload this PDF to your author area.
- The entire Online Supplement consists of the following:
- Supplemental Figures and Figure Legends (PDF file format)—optional
- Supplemental Tables and supporting information (PDF file format)—optional
- Supplemental References (PDF file format)—required
- Legends for Video files (PDF file format)—optional
- Video Files (acceptable file formats are: avi, mov, mpg at max 10 MB; if larger, create and upload zip file)—optional
- Please try to keep the individual file size to 10 MB or less to facilitate easier downloading for readers.
- The Editorial Office is not responsible for extracting Online Supplement material from print manuscript material
- All Supplemental Material should not be included in the Manuscript Text.
- Supplemental Figures/Tables/Legends must be labeled using the ROMAN NUMERAL SYSTEM (I-V).
- Cover Art Award Announcement
- Authors are encouraged to submit images for the journal cover. These will be selected by the editors based on a combination of artistic, technical, and scientific considerations.
- When a manuscript is accepted, the Editors encourage authors to submit potential figures for the cover of the journal. Potential figures can be submitted as PDF or JPEG for preview.
- The figure file should be supplied at the exact size and proportions desired for the cover. The trim size for ATVB is 8 1/8” by 10 7/8”.
- Once selected, the cover figure file must be of high resolution (minimum 600 DPI).
- Please indicate whether color figures have been supplied in CMYK or RGB.
- Preferable format is 600 dpi or higher TIF.
- These images should be related to the submitted article, but not necessarily one of the manuscript figures.
- Appropriate figures should be both aesthetically beautiful and scientifically exciting; they should be associated with the general topic of the paper, or they may be altered/enhanced versions of an original figure within the manuscript.
- Potential cover figures should have a single panel, with no labels or text of any kind. Include a brief caption (50 words max with the manuscript text.
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