Regulation of an Inflammatory Disease
Krüppel-Like Factors and Atherosclerosis
This invited review summarizes work presented in the Russell Ross lecture delivered at the 2012 proceedings of the American Heart Association. We begin with a brief overview of the structural, cellular, and molecular biology of Krüppel-like factors. We then focus on discoveries during the past decade, implicating Krüppel-like factors as key determinants of vascular cell function in atherosclerotic vascular disease.
- Received September 30, 2013.
- Accepted January 7, 2014.
- © 2014 American Heart Association, Inc.