Abstract 519: Consumption of Energy Beverage is Associated With an Attenuation of Arterial Endothelial Flow--Mediated Dilatation
Introduction: Energy drinks are being consumed more and more worldwide, and have been associated with some deaths in adolescents and young adults, especially when consumed while exercising. The consumption of energy drinks before or during exercise might be linked to an increased risk for myocardial ischemia as a symptom of endothelial dysfunction. Energy beverage consumption and its acute effect on endothelial function is not well-studied.
Consumption of an energy drink will acutely impair endothelial function in a young healthy adult.
Methods: After fasting from caffeine for at least 24 h and food for at least 8 h prior, eleven healthy non-smoker medical students (9 males), average age 24.5 years (range 23-27 years), average BMI 22.8, received an ECG, blood pressure & pulse check, and underwent baseline testing (BL) of endothelial function using the technique of endothelium-dependent flow-mediated dilatation (FMD) with high-resolution ultrasound (according to recommended guidelines of the University of Wisconsin Atherosclerosis Imaging Research Program Core Laboratory). The subjects then drank an energy beverage (EB), a 24-oz can of Monster Energy Drink®, and the above was repeated at 90 min after consumption. The FMD was calculated as the ratio between the post-cuff release diameter and the baseline diameter. Each FMD image was checked for quality control, and each artery diameter was measured as the distance between opposing tunica medias by two experts. Three measurements were taken at the QRS complex, repeated on three separate beats, and then all were averaged.
Results: The hemodynamics were as follows, BL vs EB group respectively (mean+/-SD): Heart rate 65.2+/-11.3 vs 68.2+/-11.8 beats per minute, Systolic Blood pressure 114.0+/-10.4 vs. 114.1+/-10.4 mmHg, Diastolic blood pressure 68.8+/-9.3 vs. 70.6+/-7.1 mmHg; all were not significantly different. However, consumption of the EB resulted in a significantly attenuated peak FMD response (mean+/-SD): BL group 5.9+/-4.6% vs. EB group 1.9+/-2.1%; P=0.03).
Conclusions: Acute exposure to an energy beverage impairs arterial endothelial function in healthy young adults. Given the increased use of these beverages associated with exercise in young adults, more research is needed.
Author Disclosures: J. Higgins: None. B. Yang: None. B. Ortiz: None. N. Herrin: None. J. Doolittle: None. K. Kahlden: None. T. Dayah: None. D. Cassel: None. A. Ali: None.
- © 2014 by American Heart Association, Inc.