Abstract 307: Estimation of Femoral Arterial Diameters in Men and Women Using New Postprocessing MR Angiographic Fly-Through Technique
Background and Purpose: Development of the human vasculature database including femoral arterial parameters like maximum femoral artery diameter (MFAD), length, branching angles, etc for both men and women will be critical for Peripheral Arterial Disease (PAD) diagnosis for a treating clinician. Sporadic or limited work has been reported in clinical/pre-clinical research till date. This work was an important effort towards the development of human vasculature database using our newly developed method for estimation of stenosis1.
Methods: Patient exams were performed under an IRB-approved protocol. Raw MR angiographic images of 30 male & 30 female PAD patients were retrospectively processed and analyzed for MFAD. The measurement includes healthy as well as symptomatic regions of interest at different femoral arterial sections. MR angiographies with 1mm3 spatial resolution were used for this work. Clinical exams were acquired on 3.0 T scanners (GE, DVMR 20.1IB, Milwaukee, WI).
Data analysis: The angiogram was post-processed using tree analysis and virtual endoscopy modules of Analyze 11.0 software (Analyze 11.0; Biomedical Imaging Resource, Mayo Clinic, Rochester, MN) to fly through the femoral artery. A statistical parameter called Brightness Area Product (BAP) was defined as the sum of the intensities above the sample minimum intensity/threshold set by the user. This BAP is treated as a metric for the assessment of degree of stenosis. Different parameters were tested using 2-way Anova student t-test.
Results and Discussions: A statistical significance (p<0.05) has been noticed for MFAD and linear arterial measurements among men and women for both healthy and symptomatic sections of the peripheral artery. More work towards the development and validation of this study is under progress.
New Reconstruction Technique for MRA to "Fly Through" the Lumen of the Cerebral Vasculature Mallikarjunarao Kasam; Siva S Ketha; Soumya Konduru, ATVB 2013, FL, USA, Abstract 273.
Author Disclosures: M. Kasam: None.
- © 2014 by American Heart Association, Inc.