Abstract 415: Lipid Profiles in Minority and Non-Minority Veterans following Percutaneous Coronary Intervention
Background Lipid lowering therapy is an established core measure of secondary prevention in coronary artery disease management. The National Cholesterol Education Program - Adult treatment panel III (NCEP ATPIII) guidelines recommend a goal low density lipoprotein (LDL) level less than 100 mg/dL for CAD management. Statins remain the preferred agent for LDL reduction. It is unclear whether race plays a role in lipid control.
Methods We conducted a retrospective, observational study on all patients undergoing PCI at an urban veterans hospital from September 2004 to December 2011. Statin use and lipid profiles at six months post-PCI were compared to pre-PCI values between minorities and non-minorities.
Results A total of 1052 patients (60% minorities of which 88% were African American) were analyzed. The mean LDL decreased at six-month follow up in both groups. The mean LDL decreased by 15.2 mg/dL in the minority group and by 15.1 mg/dL in the non-minority group (p<0.0001). The percentage of patients at LDL goals of <100 mg/dL pre-PCI and at six month follow-up increased from 56% to 74% in the minority group (p<0.0001), respectively, and from 64% to 78% in the non-minority group (p=0.0002), respectively. The percentage of patients on a statin pre-PCI and at six-month follow up increased from 69% to 90% in the minority group (p<0.0001), respectively, and 72% to 86% in the non-minority group (p<0.0001), respectively.
Conclusion Both groups exhibited an improvement in LDL levels six months after PCI and while on statin therapy. The mean difference was equivalent for minorities and non-minorities. This improvement was also reflected in the increased proportion of patients meeting ATPIII guidelines in both groups. There was also an increase in the usage of statin therapy in both groups at six months; however, the minority subgroup displayed a greater increase in statin use when compared to the non-minority subgroup.
- © 2013 by American Heart Association, Inc.