Abstract 252: Method to Quantify Femoropopliteal Artery Deformation During Knee Flexion
Introduction High failure rates of femoropopliteal reconstructions are commonly attributed to deformations and forces exerted on the artery during movement. The purpose of this study was to develop a method to better quantify these deformations.
Methods Custom-made stainless steel markers were deployed in an in situ cadaveric femoropopliteal artery. The artery was then infused with contrast and CT images of the straight and bent (45°, 90°, 135°) leg were acquired. 3D reconstructions of the leg were created using Mimics and identification of the marker position and geometry enabled measurements of axial extension, compression, bending and torsion. After imaging, the artery was surgically exposed, photographed and excised for histological analysis.
Results The femoropopliteal artery deformed non-uniformly along its length. No changes with knee flexion were seen proximal to the adductor hiatus and radial compression was minimal throughout the length of the artery. At the adductor hiatus the artery experienced 45° angle of twist, but no axial compression or bending. Distally, buckling and axial compression (36%) were demonstrated, but no torsion. Histology demonstrated intimal thickening corresponding to areas with the largest deformations (Figure 1).
Conclusions This method allows quantification of non-uniform arterial deformation in the femoropopliteal artery with knee flexion. This information may assist in the design of better reconstruction techniques and devices for treatment of femoropopliteal arterial disease.
- © 2013 by American Heart Association, Inc.