Abstract 436: Assessing Statin Therapy and Lipid Profile Goals 6 Months After Percutaneous Coronary Intervention at a Veterans Hospital
Background: Lipid lowering therapy is an established core measure of secondary prevention in coronary artery disease (CAD) management. The National Cholesterol Education Program - Adult treatment panel III (NCEP-ATP III) advises a minimum LDL level less than 100 mg/dL in patients with CAD and a recommended LDL less than 70 mg/dL for high risk patients. Statins remain the preferred agent for LDL reduction.
Methods: We conducted a retrospective, observational study on all patients undergoing PCI at an urban Veterans Hospital from September 2004 to January 2011. Statin use and lipid profiles at 6 months post-PCI were compared to pre-PCI values.
Results: A total of 933 unique patients had PCI during the study period. The mean total cholesterol decreased 18 mg/dL and the mean LDL decreased 15 mg/dL during 6 months follow-up (p< 0.001) (refer to table). The mean HDL did not differ significantly. The percent of patients at NCEP-ATP III guideline’s goal of LDL < 100 mg/dL increased from 58% pre-PCI to 74% post-PCI. Goal LDL < 70 mg/dL increased from 22 to 31% at 6 months. The use of statins increased from 69% to 89%.
Conclusion: There were significant improvements in total cholesterol and LDL values at six months post-PCI, as well as the percentage of patients who met the NCEP-ATP III recommended goal of LDL cholesterol less than 100 mg/dL and the suggested goal of 70 mg/dL. At six months, there was an increase usage of statin therapy.
- © 2012 by American Heart Association, Inc.