Correction

Treatment of floxed mice with Srebp-1c ASO before acute depletion of hepatic Pten blocks the increase in hepatic triglycerides (TG) but does not result in decreased apolipoprotein B (apoB) secretion. Floxed mice were pretreated for 4 weeks with Srebp-1c ASO before being injected with recombinant adenovirus containing either Cre (Cre) or Gfp (GFP). Studies were performed 4 days after injection of virus. A, Insulin signaling was increased significantly in mice receiving Cre adenovirus as assessed by the phospho-v-akt murine thymoma viral oncogene homolog (AKT), (p-AKT)/AKT ratio. B, Srebp-1c and Fas gene expression were not increased in ASO-pretreated mice receiving Cre adenovirus. C, Hepatic TG levels were not significantly increased and were in the normal range in ASO-pretreated mice receiving Cre adenovirus. D, TG secretion was not significantly increased in ASO-pretreated mice receiving Cre adenovirus. E and F, Secretion rates of apoB100 and apoB48 were not affected in ASO-pretreated mice receiving Cre adenovirus. n=3 for each group. *P<0.01.