The Fibronectin RGD Motif Is Required for Multiple Angiogenic Events During Early Embryonic Development
In the present study we demonstrated that inactivation of the RGD motif in mice results in a severe circulation defect that differs from the defect seen in mice lacking FN. Our findings indicate that FN is essential for both vasculogenesis and angiogenesis, and the RGD motif plays specific roles in angiogenesis.
For the paper by Seiichiro Takahashi, Markus Moser, Eloi Montanez, Takanari Nakano, Makoto Seo, Steffen Backert, Ikuo Inoue, Takuya Awata, Sigehiro Katayama, Tsugikazu Komoda, and Reinhard Fässler (The fibronectin RGD motif is required for multiple angiogenic events during early embryonic development. Arterioscler Thromb Vasc Biol. 2009 August 27 [Epub ahead of print]; DOI: 10.1161/ATVBAHA.108.181164), after an investigation by the Saitama Medical University Internal Investigation Committee, the Committee concluded that it was unethical for Dr. Takahashi to publish this paper for the following reasons:
Dr. Takahashi admitted that he forged the signatures of coauthors Markus Moser, Eloi Montanez, and Reinhard Fässler that appeared on the Authorship Responsibility and Copyright Transfer Agreement.
Signatures of the other coauthors were made by themselves, not by Dr. Takahashi.
None of the Japanese coauthors knew before publication that the signatures of Dr. Moser, Dr. Montanez, and Dr. Fässler were forged by Dr. Takahashi.
None of the coauthors advised Dr. Takahashi that the signatures of Dr. Moser, Dr. Montanez, and Dr. Fässler should be faked by Dr. Takahashi.
Neither Dr. Moser, Dr. Montanez, nor Dr. Fässler read the submitted version of original manuscript.
Some of the Japanese coauthors did not check the boxes that appear on 1-E of the Authorship Responsibility and Copyright Transfer Agreement. In such cases, Dr. Takahashi did that instead, without permission.
Dr. Takahashi sent an e-mail message to Dr. Moser, Dr. Montanez, and Dr. Fässler, using fake e-mail addresses, to pretend that the German coauthors knew about the paper. Some of the Japanese coauthors believed this message and signed the Authorship Responsibility and Copyright Transfer Agreement.
The editors, therefore, hereby retract the paper.