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ARTICLES

The insulin resistance syndrome in smokers is related to smoking habits.

B Eliasson, S Attvall, M R Taskinen, U Smith
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https://doi.org/10.1161/01.ATV.14.12.1946
Arteriosclerosis, Thrombosis, and Vascular Biology. 1994;14:1946-1950
Originally published December 1, 1994
B Eliasson
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S Attvall
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M R Taskinen
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U Smith
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Abstract

The relationship between smoking habits, insulin resistance, and related risk factors for cardiovascular disease was examined in 57 middle-aged male smokers whose degree of insulin resistance was quantified by using the euglycemic clamp technique. Smoking habits correlated with degree of insulin resistance and consequently with various manifestations of the insulin resistance syndrome including levels of insulin, high-density lipoprotein cholesterol, triglycerides, and plasminogen activator inhibitor-1 (PAI-1) activity. Smoking habits, independent of degree of insulin resistance, were also related to levels of total cholesterol and low-density lipoprotein cholesterol as well as triglycerides. Stepwise regression analyses considering the effects of age, lean body mass, body fat, body mass index, waist/hip ratio, and alcohol consumption showed that only smoking habits and percent body fat were independently related to degree of insulin resistance. This study shows that insulin resistance and the insulin resistance syndrome are important but not unique contributors to the strong risk profile for cardiovascular disease in middle-aged men who smoke.

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Arteriosclerosis, Thrombosis, and Vascular Biology
December 1994, Volume 14, Issue 12
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    The insulin resistance syndrome in smokers is related to smoking habits.
    B Eliasson, S Attvall, M R Taskinen and U Smith
    Arteriosclerosis, Thrombosis, and Vascular Biology. 1994;14:1946-1950, originally published December 1, 1994
    https://doi.org/10.1161/01.ATV.14.12.1946

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    The insulin resistance syndrome in smokers is related to smoking habits.
    B Eliasson, S Attvall, M R Taskinen and U Smith
    Arteriosclerosis, Thrombosis, and Vascular Biology. 1994;14:1946-1950, originally published December 1, 1994
    https://doi.org/10.1161/01.ATV.14.12.1946
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