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(Arteriosclerosis, Thrombosis, and Vascular Biology. 2000;20:899.)
© 2000 American Heart Association, Inc.

ATVB Electronic Pages

ATVB Online Only

March 2000

Donald D. Heistad, Editor-in-Chief
ATVB is pleased to announce that some articles will now be published online only. Articles published online only will undergo the same review process as papers in the printed journal. Publication online only will allow those articles to be published more rapidly and also will allow the journal to publish more papers.

Articles published online will be identified by ( ) in the Table of Contents. The abstract will be published in the print issue, and the full-length article can be accessed at www.atvbaha.org. Articles will be cited in the same way as other papers and will be indexed in MEDLINE, Index Medicus, and other indexing services.

We anticipate that online only publication, after a rigorous review process, will grow rapidly. We will appreciate feedback and suggestions from readers and authors during the early months of this experiment.

Ras/Rac-Dependent Activation of p38 Mitogen-Activated Protein Kinases in Smooth Muscle Cells Stimulated by Cyclic Strain Stress

Chaohong Li, Yanhua Hu, Gertraud Sturm, Georg Wick, Qingbo Xu

Abstract—p38, a subfamily of the mitogen-activated protein kinases (MAPKs), is a crucial signal transducer between a variety of extracellular stimuli and gene expression in mammalian cells. This kinase is activated in cultured cells stimulated by heat shock, osmotic stress, and proinflammatory cytokines, but a similar activation of p38 MAPKs in vascular smooth muscle cells (SMCs) stimulated by mechanical stress has yet to be studied. We studied signal pathways leading to time- and strength-dependent p38 activation in rat SMCs in response to cyclic strain stress. p38 . . . [Full Text of this Article]