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Arteriosclerosis, Thrombosis, and Vascular Biology. 1991;11:1786-1794

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Arteriosclerosis and Thrombosis, Vol 11, 1786-1794, Copyright © 1991 by American Heart Association


ARTICLES

Relation of extent of extracranial carotid artery atherosclerosis as measured by B-mode ultrasound to the extent of coronary atherosclerosis

JL Wofford, FR Kahl, GR Howard, WM McKinney, JF Toole and JR Crouse 3d
Department of Internal Medicine, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, NC 27103.

The extent of carotid artery atherosclerosis as measured by B-mode ultrasound has been shown to be strongly and independently correlated with the presence or absence of coronary atherosclerotic disease (CAD), but no studies to date have used carotid B-mode ultrasound to compare the extent of atherosclerotic disease in the two arterial circulations. We used data from a registry of patients undergoing cardiac catheterization and B-mode ultrasound of the carotid arteries to compare the extent of CAD (number of major coronary vessels with 50% or greater stenosis as judged by a consensus interpretation) with the extent of extracranial carotid atherosclerosis. Four hundred thirty- four patients (234 men, 200 women) greater than 40 years of age were stratified by gender and then divided into quartiles on the basis of a B-mode score that was derived by summing arterial wall thickness at nine sites in the left and nine sites in the right carotid arteries. Evaluation of extent of CAD for the four B-mode quartiles showed that men in the lowest B-mode quartile were over six times more likely to have normal coronary arteries than three- to four-vessel CAD, while men in the highest B-mode quartile were over 10 times more likely to have three- to four-vessel CAD than normal coronary arteries. The findings were similar for women but not as dramatic. Gender-specific discriminant function models using traditional risk factors alone or in combination with B-mode score were developed to predict the extent of CAD.(ABSTRACT TRUNCATED AT 250 WORDS)


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CirculationHome page
M. Hosoi, Y. Nishizawa, K. Kogawa, T. Kawagishi, T. Konishi, K. Maekawa, M. Emoto, S. Fukumoto, A. Shioi, T. Shoji, et al.
Angiotensin-Converting Enzyme Gene Polymorphism Is Associated With Carotid Arterial Wall Thickness in Non–Insulin-Dependent Diabetic Patients
Circulation, August 15, 1996; 94(4): 704 - 707.
[Abstract] [Full Text]


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Arterioscler. Thromb. Vasc. Bio.Home page
M. Suurkula, B. Fagerberg, I. Wendelhag, S. Agewall, and J. Wikstrand
Atherosclerotic Disease in the Femoral Artery in Hypertensive Patients at High Cardiovascular Risk: The Value of Ultrasonographic Assessment of Intima-Media Thickness and Plaque Occurrence
Arterioscler Thromb Vasc Biol, August 1, 1996; 16(8): 971 - 977.
[Abstract] [Full Text]


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Arterioscler. Thromb. Vasc. Bio.Home page
S. Tonstad, O. Joakimsen, E. Stensland-Bugge, T. P. Leren, L. Ose, D. Russell, and K. H. Bonaa
Risk Factors Related to Carotid Intima-Media Thickness and Plaque in Children With Familial Hypercholesterolemia and Control Subjects
Arterioscler Thromb Vasc Biol, August 1, 1996; 16(8): 984 - 991.
[Abstract] [Full Text]


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StrokeHome page
C. Bonithon-Kopp, P. J. Touboul, C. Berr, C. Magne, and P. Ducimetiere
Factors of Carotid Arterial Enlargement in a Population Aged 59 to 71 Years : The EVA Study
Stroke, April 1, 1996; 27(4): 654 - 660.
[Abstract] [Full Text]


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StrokeHome page
M. A. Espeland, T. E. Craven, W. A. Riley, J. Corson, A. Romont, and C. D. Furberg
Reliability of Longitudinal Ultrasonographic Measurements of Carotid Intimal-Medial Thicknesses
Stroke, March 1, 1996; 27(3): 480 - 485.
[Abstract] [Full Text]


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Arterioscler. Thromb. Vasc. Bio.Home page
C. Bonithon-Kopp, P.-J. Touboul, C. Berr, C. Leroux, F. Mainard, D. Courbon, and P. Ducimetiere
Relation of Intima-Media Thickness to Atherosclerotic Plaques in Carotid Arteries : The Vascular Aging (EVA) Study
Arterioscler Thromb Vasc Biol, February 1, 1996; 16(2): 310 - 316.
[Abstract] [Full Text]


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CirculationHome page
M. R. Adams, A. Nakagomi, A. Keech, J. Robinson, R. McCredie, B. P. Bailey, S. B. Freedman, and D. S. Celermajer
Carotid Intima-Media Thickness Is Only Weakly Correlated With the Extent and Severity of Coronary Artery Disease
Circulation, October 15, 1995; 92(8): 2127 - 2134.
[Abstract] [Full Text]


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CirculationHome page
J. Lynch, G. A. Kaplan, R. Salonen, R. D. Cohen, and J. T. Salonen
Socioeconomic Status and Carotid Atherosclerosis
Circulation, October 1, 1995; 92(7): 1786 - 1792.
[Abstract] [Full Text]


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CirculationHome page
A. Simon, P. Giral, and J. Levenson
Extracoronary Atherosclerotic Plaque at Multiple Sites and Total Coronary Calcification Deposit in Asymptomatic Men : Association With Coronary Risk Profile
Circulation, September 15, 1995; 92(6): 1414 - 1421.
[Abstract] [Full Text]


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CirculationHome page
J. R. Crouse III, T. E. Craven, A. P. Hagaman, and M. G. Bond
Association of Coronary Disease With Segment-Specific Intimal-Medial Thickening of the Extracranial Carotid Artery
Circulation, September 1, 1995; 92(5): 1141 - 1147.
[Abstract] [Full Text]


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Arch Intern MedHome page
L. M. Prisant, P. C. Zemel, F. T. Nichols, M. B. Zemel, J. R. Sowers, A. A. Carr, W. O. Thompson, and M. G. Bond
Carotid Plaque Associations Among Hypertensive Patients
Arch Intern Med, February 22, 1993; 153(4): 501 - 506.
[Abstract] [PDF]