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Arteriosclerosis, Thrombosis, and Vascular Biology
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Published Online
on July 3, 2003

Arteriosclerosis, Thrombosis, and Vascular Biology. 2003
Published online before print July 3, 2003, doi: 10.1161/01.ATV.0000084827.77945.66
A more recent version of this article appeared on September 1, 2003
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*Blood Thinners
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Right arrow Anticoagulant mechanisms
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Submitted on May 9, 2003
Accepted on June 19, 2003

Emerging Anticoagulant Drugs

Shannon M. Bates and Jeffrey I. Weitz *

From the Department of Medicine (S.M.B., J.I.W.), McMaster University and Henderson Research Centre (J.I.W.), Hamilton, Ontario, Canada.

* To whom correspondence should be addressed. E-mail: jweitz{at}thrombosis.hhscr.org.

Abstract--The limitations of traditional anticoagulants, heparin and warfarin, have prompted the development of new anticoagulant drugs for prevention and treatment of both venous and arterial thromboembolism. After a brief review of thrombogenesis and its regulation, this study focuses on new anticoagulant agents in more advanced stages of clinical testing.
Key words: anticoagulant • antithrombotic • venous thromboembolism • arterial thromboembolism • direct thrombin inhibitor




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