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(Arteriosclerosis, Thrombosis, and Vascular Biology. 2005;25:478.)
© 2005 American Heart Association, Inc.

Editorials

Recommendations for Blood Pressure Measurement in Animals

Summary of an AHA Scientific Statement From the Council on High Blood Pressure Research, Professional and Public Education Subcommittee

Theodore W. Kurtz; Karen A. Griffin; Anil K. Bidani; Robin L. Davisson; John E. Hall

From the Department of Laboratory Medicine (T.W.K.), University of California, San Francisco; the Department of Internal Medicine (K.A.G., A.K.B.), Loyola University & Hines VA Hospital, Maywood, Ill; the Department of Anatomy and Cell Biology (R.L.D.), University of Iowa, Iowa City; and the Department of Physiology and Biophysics (J.E.H.), University of Mississippi, Jackson.

Correspondence to Theodore W. Kurtz, MD, Professor of Laboratory Medicine, University of California, San Francisco, Box 0134, 185 Berry Street, Suite 290, San Francisco, CA 94107. E-mail KurtzT@Labmed2.ucsf.edu

An extract of the first 250 words of the full text is provided, because this article has no abstract.

Accurate and meaningful measurements of blood pressure (BP) are often critical to the interpretation of studies of vascular biology, atherosclerosis, and other forms of cardiovascular disease. Although many research scientists have embraced advanced molecular technologies for studying cardiovascular function and disease pathogenesis, a surprising number of the same investigators continue to use suboptimal techniques for measuring BP in experimental animals. To address this problem and assist investigators in selecting optimal methods for BP monitoring, the American Heart Association (AHA) has developed a scientific statement on recommendations for BP measurement in experimental animals. These recommendations for BP measurement are briefly summarized in this article. The complete text and discussion of the recommendations are published online in Arteriosclerosis, Thrombosis, and Vascular Biology as well as in print in other AHA journals.¹ Comprehensive recommendations for BP measurement in humans have also been developed and are published in the AHA journal Hypertension.²

See page e22

BP Measurement Methods

The techniques for measuring BP in experimental animals have improved considerably over the past decade, and several methods are available that allow routine monitoring of BP profiles throughout the day and night over prolonged periods of time in conscious, unrestrained, unstressed animals. Techniques for measuring BP in experimental animals can be divided into indirect methods and direct methods, and the technical details of these methods along with their advantages and disadvantages are discussed in the full report.¹ The most commonly used indirect method for monitoring BP is the cuff technique, in which BP is measured in a tail . . . [Full Text of this Article]

Related Article:

Recommendations for Blood Pressure Measurement in Humans and Experimental Animals: Part 2: Blood Pressure Measurement in Experimental Animals. A Statement for Professionals From the Subcommittee of Professional and Public Education of the American Heart Association Council on High Blood Pressure Research

Theodore W. Kurtz, Karen A. Griffin, Anil K. Bidani, Robin L. Davisson, and John E. Hall
Arterioscler Thromb Vasc Biol 2005 25: e22-e33. [Abstract] [Full Text] [PDF]

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