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(Arteriosclerosis, Thrombosis, and Vascular Biology. 2005;25:1321.)
© 2005 American Heart Association, Inc.

Brief Reviews

New Links Between Inflammation and Thrombosis

Denisa D. Wagner

From the CBR Institute for Biomedical Research and Department of Pathology, Harvard Medical School, Boston, Mass.

Correspondence to Denisa D. Wagner, CBR Institute for Biomedical Research, 800 Huntington Ave, Boston, MA 02115. E-mail wagner{at}cbr.med.harvard.edu

This article is a summary of the Sol Sherry Lecture of the Council on Arteriosclerosis, Thrombosis, and Vascular Biology, which was presented at the Scientific Sessions of the American Heart Association in November 2004. It highlights work from our laboratory, focusing mainly on new aspects of P-selectin and CD40L (CD154) biology and on the interplay of platelets and leukocytes in thrombosis and inflammation.

This article is a summary of the Sol Sherry Lecture of the Council on Arteriosclerosis, Thrombosis, and Vascular Biology, which was presented at the Scientific Sessions of the American Heart Association in November 2004. The article focuses mainly on new aspects of P-selectin and CD40L (CD154) biology and on the interplay of platelets and leukocytes in thrombosis and inflammation.

Key Words: platelets • inflammation • adhesion molecules • Weibel-Palade body

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