This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Kurtz, T. W. Articles by Hall, J. E. Search for Related Content PubMed PubMed Citation Articles by Kurtz, T. W. Articles by Hall, J. E. Related Collections Animal models of human disease Hypertension - basic studies Related Article

(Arteriosclerosis, Thrombosis, and Vascular Biology. 2005;25:e22.)
© 2005 American Heart Association, Inc.

AHA Scientific Statement

Recommendations for Blood Pressure Measurement in Humans and Experimental Animals

Part 2: Blood Pressure Measurement in Experimental Animals. A Statement for Professionals From the Subcommittee of Professional and Public Education of the American Heart Association Council on High Blood Pressure Research

Theodore W. Kurtz, MD; Karen A. Griffin, MD; Anil K. Bidani, MD; Robin L. Davisson, PhD; John E. Hall, PhD
In experimental animals, as in humans, techniques for measuring blood pressure (BP) have improved considerably over the past decade. In this document, we present recommendations for measuring BP in experimental animals with the goal of helping investigators select optimal methods for BP monitoring in the research laboratory. The advantages and disadvantages of various BP measurement methods are discussed and specific recommendations are provided for selecting the optimal technique depending on the study objective. Although indirect techniques that permit only sporadic measurements of BP may be suitable for some purposes, methods for directly measuring BP are generally preferred because of their ability to monitor the highly dynamic nature of BP in a comprehensive fashion. Selection of the methods to be used should ultimately be guided by the study objectives to insure that the techniques chosen are appropriate for the experimental questions being explored.

Key Words: blood pressure • blood pressure determination • blood pressure monitoring • hypertension, experimental

Related Article:

Recommendations for Blood Pressure Measurement in Animals: Summary of an AHA Scientific Statement From the Council on High Blood Pressure Research, Professional and Public Education Subcommittee

Theodore W. Kurtz, Karen A. Griffin, Anil K. Bidani, Robin L. Davisson, and John E. Hall
Arterioscler. Thromb. Vasc. Biol. 2005 25: 478-479. [Full Text] [PDF]

This article has been cited by other articles:

				A. Schulz, J. Hansch, K. Kuhn, M. Schlesener, P. Kossmehl, J. R. Nyengaard, N. Wendt, M. Huber, and R. Kreutz Nephron deficit is not required for progressive proteinuria development in the Munich Wistar Fromter rat Physiol Genomics, September 17, 2008; 35(1): 30 - 35. [Abstract] [Full Text] [PDF]

				F. Desjardins, I. Lobysheva, M. Pelat, B. Gallez, O. Feron, C. Dessy, and J.-L. Balligand Control of blood pressure variability in caveolin-1-deficient mice: role of nitric oxide identified in vivo through spectral analysis Cardiovasc Res, August 1, 2008; 79(3): 527 - 536. [Abstract] [Full Text] [PDF]

				L. G. Sanchez-Lozada, E. Tapia, P. Bautista-Garcia, V. Soto, C. Avila-Casado, I. P. Vega-Campos, T. Nakagawa, L. Zhao, M. Franco, and R. J. Johnson Effects of febuxostat on metabolic and renal alterations in rats with fructose-induced metabolic syndrome Am J Physiol Renal Physiol, April 1, 2008; 294(4): F710 - F718. [Abstract] [Full Text] [PDF]

				A. G. Bechtold, K. Vernon, T. Hines, and D. A. Scheuer Genetic predisposition to hypertension sensitizes borderline hypertensive rats to the hypertensive effects of prenatal glucocorticoid exposure J. Physiol., January 15, 2008; 586(2): 673 - 684. [Abstract] [Full Text] [PDF]

				A. Y. Deng Positional Cloning of Quantitative Trait Loci for Blood Pressure: How Close Are We?: A Critical Perspective Hypertension, April 1, 2007; 49(4): 740 - 747. [Full Text] [PDF]

				J. Bolbrinker, S. Markovic, M. Wehland, W. B. W. H. Melenhorst, H. van Goor, and R. Kreutz Expression and Response to Angiotensin-Converting Enzyme Inhibition of Matrix Metalloproteinases 2 and 9 in Renal Glomerular Damage in Young Transgenic Rats with Renin-Dependent Hypertension J. Pharmacol. Exp. Ther., January 1, 2006; 316(1): 8 - 16. [Abstract] [Full Text] [PDF]

				T. W. Kurtz, K. A. Griffin, A. K. Bidani, R. L. Davisson, and J. E. Hall Recommendations for Blood Pressure Measurement in Animals: Summary of an AHA Scientific Statement From the Council on High Blood Pressure Research, Professional and Public Education Subcommittee Arterioscler. Thromb. Vasc. Biol., March 1, 2005; 25(3): 478 - 479. [Full Text] [PDF]