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Arteriosclerosis, Thrombosis, and Vascular Biology. 2003;23:1491-1500
Published online before print July 3, 2003, doi: 10.1161/01.ATV.0000084827.77945.66
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(Arteriosclerosis, Thrombosis, and Vascular Biology. 2003;23:1491.)
© 2003 American Heart Association, Inc.


Brief Reviews

Emerging Anticoagulant Drugs

Shannon M. Bates; Jeffrey I. Weitz

From the Department of Medicine (S.M.B., J.I.W.), McMaster University and Henderson Research Centre (J.I.W.), Hamilton, Ontario, Canada.

Correspondence to Dr Jeffrey I. Weitz, Henderson Research Centre, 711 Concession St, Hamilton, Ontario L8V 1C3, Canada. E-mail jweitz{at}thrombosis.hhscr.org

Abstract—The limitations of traditional anticoagulants, heparin and warfarin, have prompted the development of new anticoagulant drugs for prevention and treatment of both venous and arterial thromboembolism. After a brief review of thrombogenesis and its regulation, this study focuses on new anticoagulant agents in more advanced stages of clinical testing.


Key Words: anticoagulant • antithrombotic • venous thromboembolism • arterial thromboembolism • direct thrombin inhibitor




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