Donate Help Contact The AHA Sign In Home
American Heart Association
Arteriosclerosis, Thrombosis, and Vascular Biology
Search: search_blue_button Advanced Search
Arteriosclerosis, Thrombosis, and Vascular Biology. 1990;10:497-511

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowRequest Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Despres, J. P.
Right arrow Articles by Bouchard, C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Despres, J. P.
Right arrow Articles by Bouchard, C.
Right arrowPubmed/NCBI databases
*Compound via MeSH
*Substance via MeSH

Arteriosclerosis, Vol 10, 497-511, Copyright © 1990 by American Heart Association


ARTICLES

Regional distribution of body fat, plasma lipoproteins, and cardiovascular disease

JP Despres, S Moorjani, PJ Lupien, A Tremblay, A Nadeau and C Bouchard
Physical Activity Sciences Laboratory, Laval University, Ste-Foy, Quebec, Canada.

Several epidemiological studies have reported that the regional distribution of body fat is a significant and independent risk factor for cardiovascular disease (CVD) and related mortality. Although these associations are well established, the causal mechanisms are not fully understood. Numerous studies have, however, shown that specific topographic features of adipose tissue are associated with metabolic complications that are considered as risk factors for CVD such as insulin resistance, hyperinsulinemia, glucose intolerance and type II diabetes mellitus, hypertension, and changes in the concentration of plasma lipids and lipoproteins. The present article summarizes the evidence on the metabolic correlates of body fat distribution. Potential mechanisms for the association between body fat distribution, metabolic complications, and CVD are reviewed, with an emphasis on plasma lipoprotein levels and plasma lipid transport. From the evidence available, it seems likely that subjects with visceral obesity represent the subgroup of obese individuals with the highest risk for CVD. Although body fat distribution is now considered as a more significant risk factor for CVD and related death rate than obesity per se, further research is clearly needed to identify the determinants of body fat distribution and the causal mechanisms involved in the metabolic alterations. It appears certain, however, that an altered plasma lipid transport is a significant component of the relation between body fat distribution and CVD.


This article has been cited by other articles:


Home page
Arterioscler. Thromb. Vasc. Bio.Home page
S. B. Police, S. E. Thatcher, R. Charnigo, A. Daugherty, and L. A. Cassis
Obesity Promotes Inflammation in Periaortic Adipose Tissue and Angiotensin II-Induced Abdominal Aortic Aneurysm Formation
Arterioscler Thromb Vasc Biol, October 1, 2009; 29(10): 1458 - 1464.
[Abstract] [Full Text] [PDF]


Home page
Eur Heart JHome page
K. A.A. Fox, J.-P. Despres, A.-J. Richard, S. Brette, J. E. Deanfield, and on behalf of the IDEA Steering Committee and Natio
Does abdominal obesity have a similar impact on cardiovascular disease and diabetes? A study of 91 246 ambulant patients in 27 European Countries
Eur. Heart J., September 23, 2009; (2009) ehp371v1.
[Abstract] [Full Text] [PDF]


Home page
AJPHHome page
H. E. R. Hunte and D. R. Williams
The Association Between Perceived Discrimination and Obesity in a Population-Based Multiracial and Multiethnic Adult Sample
Am J Public Health, July 1, 2009; 99(7): 1285 - 1292.
[Abstract] [Full Text] [PDF]


Home page
HeartHome page
J.-P. Despres
Targeting abdominal obesity and the metabolic syndrome to manage cardiovascular disease risk
Heart, July 1, 2009; 95(13): 1118 - 1124.
[Full Text] [PDF]


Home page
Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
K. Guo, J. Mogen, S. Struzzi, and Y. Zhang
Preadipocyte transplantation: an in vivo study of direct leptin signaling on adipocyte morphogenesis and cell size
Am J Physiol Regulatory Integrative Comp Physiol, May 1, 2009; 296(5): R1339 - R1347.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Clin. Nutr.Home page
J. A Alvarez, P. B Higgins, R. A Oster, J. R Fernandez, B. E Darnell, and B. A Gower
Fasting and postprandial markers of inflammation in lean and overweight children
Am. J. Clinical Nutrition, April 1, 2009; 89(4): 1138 - 1144.
[Abstract] [Full Text] [PDF]


Home page
Arterioscler. Thromb. Vasc. Bio.Home page
J.-P. Despres, R. Ross, G. Boka, N. Almeras, I. Lemieux, and for the ADAGIO-Lipids Investigators
Effect of Rimonabant on the High-Triglyceride/ Low-HDL-Cholesterol Dyslipidemia, Intraabdominal Adiposity, and Liver Fat: The ADAGIO-Lipids Trial
Arterioscler Thromb Vasc Biol, March 1, 2009; 29(3): 416 - 423.
[Abstract] [Full Text] [PDF]


Home page
Nutr Clin PractHome page
R. Ness-Abramof and C. M. Apovian
Waist Circumference Measurement in Clinical Practice
Nutr Clin Pract, August 1, 2008; 23(4): 397 - 404.
[Abstract] [Full Text] [PDF]


Home page
MutagenesisHome page
M. Staruchova, A. R. Collins, K. Volkovova, C. Mislanova, Z. Kovacikova, J. Tulinska, A. Kocan, L. Staruch, L. Wsolova, and M. Dusinska
Occupational exposure to mineral fibres. Biomarkers of oxidative damage and antioxidant defence and associations with DNA damage and repair
Mutagenesis, July 1, 2008; 23(4): 249 - 260.
[Abstract] [Full Text] [PDF]


Home page
Arterioscler. Thromb. Vasc. Bio.Home page
J.-P. Despres, I. Lemieux, J. Bergeron, P. Pibarot, P. Mathieu, E. Larose, J. Rodes-Cabau, O. F. Bertrand, and P. Poirier
Abdominal Obesity and the Metabolic Syndrome: Contribution to Global Cardiometabolic Risk
Arterioscler Thromb Vasc Biol, June 1, 2008; 28(6): 1039 - 1049.
[Abstract] [Full Text] [PDF]


Home page
Diabetes CareHome page
F. E. Hirai, S. E. Moss, B. E.K. Klein, and R. Klein
Relationship of Glycemic Control, Exogenous Insulin, and C-Peptide Levels to Ischemic Heart Disease Mortality Over a 16-Year Period in People With Older-Onset Diabetes: The Wisconsin Epidemiologic Study of Diabetic Retinopathy (WESDR)
Diabetes Care, March 1, 2008; 31(3): 493 - 497.
[Abstract] [Full Text] [PDF]


Home page
Eur Heart J SupplHome page
J.-P. Despres, P. Poirier, J. Bergeron, A. Tremblay, I. Lemieux, and N. Almeras
From individual risk factors and the metabolic syndrome to global cardiometabolic risk
Eur. Heart J. Suppl., March 1, 2008; 10(suppl_B): B24 - B33.
[Abstract] [Full Text] [PDF]


Home page
The Diabetes EducatorHome page
P. Hollander
Cardiometabolic Risk Factors and Visceral Adipose Tissue
The Diabetes Educator, March 1, 2008; 34(Supplement_2): 37S - 41S.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
B. Balkau, J. E. Deanfield, J.-P. Despres, J.-P. Bassand, K. A.A. Fox, S. C. Smith Jr, P. Barter, C.-E. Tan, L. Van Gaal, H.-U. Wittchen, et al.
International Day for the Evaluation of Abdominal Obesity (IDEA): A Study of Waist Circumference, Cardiovascular Disease, and Diabetes Mellitus in 168 000 Primary Care Patients in 63 Countries
Circulation, October 23, 2007; 116(17): 1942 - 1951.
[Abstract] [Full Text] [PDF]


Home page
Eur Heart JHome page
Authors/Task Force Members, I. Graham, D. Atar, K. Borch-Johnsen, G. Boysen, G. Burell, R. Cifkova, J. Dallongeville, G. De Backer, S. Ebrahim, et al.
European guidelines on cardiovascular disease prevention in clinical practice: executive summary: Fourth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (Constituted by representatives of nine societies and by invited experts)
Eur. Heart J., October 1, 2007; 28(19): 2375 - 2414.
[Full Text] [PDF]


Home page
Am. J. Clin. Nutr.Home page
M. W Peeters, G. P Beunen, H. H Maes, R. J. Loos, A. L Claessens, R. Vlietinck, and M. A Thomis
Genetic and environmental determination of tracking in subcutaneous fat distribution during adolescence
Am. J. Clinical Nutrition, September 1, 2007; 86(3): 652 - 660.
[Abstract] [Full Text] [PDF]


Home page
Diabetes CareHome page
B. Balkau, P. Picard, S. Vol, L. Fezeu, E. Eschwege, and for the DESIR Study Group
Consequences of Change in Waist Circumference on Cardiometabolic Risk Factors Over 9 Years: Data from an Epidemiological Study on the Insulin Resistance Syndrome (DESIR)
Diabetes Care, July 1, 2007; 30(7): 1901 - 1903.
[Full Text] [PDF]


Home page
Am. J. Physiol. Endocrinol. Metab.Home page
K. Azuma, L. K. Heilbronn, J. B. Albu, S. R. Smith, E. Ravussin, D. E. Kelley, and and the Look AHEAD Adipose Research Group
Adipose tissue distribution in relation to insulin resistance in type 2 diabetes mellitus
Am J Physiol Endocrinol Metab, July 1, 2007; 293(1): E435 - E442.
[Abstract] [Full Text] [PDF]


Home page
Epidemiol RevHome page
G. Vazquez, S. Duval, D. R. Jacobs Jr., and K. Silventoinen
Comparison of Body Mass Index, Waist Circumference, and Waist/Hip Ratio in Predicting Incident Diabetes: A Meta-Analysis
Epidemiol. Rev., May 10, 2007; (2007) mxm008v1.
[Abstract] [Full Text] [PDF]


Home page
Eur Heart JHome page
L. de Koning, A. T. Merchant, J. Pogue, and S. S. Anand
Waist circumference and waist-to-hip ratio as predictors of cardiovascular events: meta-regression analysis of prospective studies
Eur. Heart J., April 2, 2007; (2007) ehm026v1.
[Abstract] [Full Text] [PDF]


Home page
DiabetesHome page
L. Fontana, J. C. Eagon, M. E. Trujillo, P. E. Scherer, and S. Klein
Visceral Fat Adipokine Secretion Is Associated With Systemic Inflammation in Obese Humans
Diabetes, April 1, 2007; 56(4): 1010 - 1013.
[Abstract] [Full Text] [PDF]


Home page
J EndocrinolHome page
K. Blouin, C. Richard, G. Brochu, F.-S. Hould, S. Lebel, S. Marceau, S. Biron, V. Luu-The, and A. Tchernof
Androgen inactivation and steroid-converting enzyme expression in abdominal adipose tissue in men
J. Endocrinol., December 1, 2006; 191(3): 637 - 649.
[Abstract] [Full Text] [PDF]


Home page
PediatricsHome page
C. Li, E. S. Ford, A. H. Mokdad, and S. Cook
Recent Trends in Waist Circumference and Waist-Height Ratio Among US Children and Adolescents
Pediatrics, November 1, 2006; 118(5): e1390 - e1398.
[Abstract] [Full Text] [PDF]


Home page
DiabetesHome page
S. D. Bailey, J C. Loredo-Osti, P. Lepage, J. Faith, J. Fontaine, K. M. Desbiens, T. J. Hudson, C. Bouchard, D. Gaudet, L. Perusse, et al.
Common Polymorphisms in the Promoter of the Visfatin Gene (PBEF1) Influence Plasma Insulin Levels in a French-Canadian Population.
Diabetes, October 1, 2006; 55(10): 2896 - 2902.
[Abstract] [Full Text] [PDF]


Home page
DiabetesHome page
A. Tchernof, C. Belanger, A.-S. Morisset, C. Richard, J. Mailloux, P. Laberge, and P. Dupont
Regional differences in adipose tissue metabolism in women: minor effect of obesity and body fat distribution.
Diabetes, May 1, 2006; 55(5): 1353 - 1360.
[Abstract] [Full Text] [PDF]


Home page
GutHome page
C-J Tsai, M F Leitzmann, W C Willett, and E L Giovannucci
Central adiposity, regional fat distribution, and the risk of cholecystectomy in women
Gut, May 1, 2006; 55(5): 708 - 714.
[Abstract] [Full Text] [PDF]


Home page
EndocrinologyHome page
F. Kreier, Y. S. Kap, T. C. Mettenleiter, C. van Heijningen, J. van der Vliet, A. Kalsbeek, H. P. Sauerwein, E. Fliers, J. A. Romijn, and R. M. Buijs
Tracing from Fat Tissue, Liver, and Pancreas: A Neuroanatomical Framework for the Role of the Brain in Type 2 Diabetes
Endocrinology, March 1, 2006; 147(3): 1140 - 1147.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Clin. Nutr.Home page
D. Canoy, N. Wareham, A. Welch, S. Bingham, R. Luben, N. Day, and K.-T. Khaw
Plasma ascorbic acid concentrations and fat distribution in 19 068 British men and women in the European Prospective Investigation into Cancer and Nutrition Norfolk cohort study
Am. J. Clinical Nutrition, December 1, 2005; 82(6): 1203 - 1209.
[Abstract] [Full Text] [PDF]


Home page
NEJMHome page
J.-P. Despres, A. Golay, L. Sjostrom, and the Rimonabant in Obesity-Lipids Study Group
Effects of Rimonabant on Metabolic Risk Factors in Overweight Patients with Dyslipidemia
N. Engl. J. Med., November 17, 2005; 353(20): 2121 - 2134.
[Abstract] [Full Text] [PDF]


Home page
J. Appl. Physiol.Home page
N. M. Punjabi and V. Y. Polotsky
Disorders of glucose metabolism in sleep apnea
J Appl Physiol, November 1, 2005; 99(5): 1998 - 2007.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
J.-P. Despres
Our Passive Lifestyle, Our Toxic Diet, and the Atherogenic/Diabetogenic Metabolic Syndrome: Can We Afford to Be Sedentary and Unfit?
Circulation, July 26, 2005; 112(4): 453 - 455.
[Full Text] [PDF]


Home page
Am. J. Clin. Nutr.Home page
J. L Kuk, S. Lee, S. B Heymsfield, and R. Ross
Waist circumference and abdominal adipose tissue distribution: influence of age and sex
Am. J. Clinical Nutrition, June 1, 2005; 81(6): 1330 - 1334.
[Abstract] [Full Text] [PDF]


Home page
J. Clin. Endocrinol. Metab.Home page
G. Ferretti, T. Bacchetti, C. Moroni, S. Savino, A. Liuzzi, F. Balzola, and V. Bicchiega
Paraoxonase Activity in High-Density Lipoproteins: A Comparison between Healthy and Obese Females
J. Clin. Endocrinol. Metab., March 1, 2005; 90(3): 1728 - 1733.
[Abstract] [Full Text] [PDF]


Home page
Arterioscler. Thromb. Vasc. Bio.Home page
M. Okazaki, S. Usui, M. Ishigami, N. Sakai, T. Nakamura, Y. Matsuzawa, and S. Yamashita
Identification of Unique Lipoprotein Subclasses for Visceral Obesity by Component Analysis of Cholesterol Profile in High-Performance Liquid Chromatography
Arterioscler Thromb Vasc Biol, March 1, 2005; 25(3): 578 - 584.
[Abstract] [Full Text] [PDF]


Home page
Clin. Chem.Home page
D. C. Chan, G. F. Watts, T. W.K. Ng, Y. Uchida, N. Sakai, S. Yamashita, and P. H. R. Barrett
Adiponectin and other Adipocytokines as Predictors of Markers of Triglyceride-Rich Lipoprotein Metabolism
Clin. Chem., March 1, 2005; 51(3): 578 - 585.
[Abstract] [Full Text] [PDF]


Home page
J. Lipid Res.Home page
M.-T. Berthier, A. Houde, M. Cote, A.-M. Paradis, P. Mauriege, J. Bergeron, D. Gaudet, J.-P. Despres, and M.-C. Vohl
Impact of adiponectin gene polymorphisms on plasma lipoprotein and adiponectin concentrations of viscerally obese men
J. Lipid Res., February 1, 2005; 46(2): 237 - 244.
[Abstract] [Full Text] [PDF]


Home page
J. Clin. Endocrinol. Metab.Home page
K. K. Miller, B. M. K. Biller, J. G. Lipman, G. Bradwin, N. Rifai, and A. Klibanski
Truncal Adiposity, Relative Growth Hormone Deficiency, and Cardiovascular Risk
J. Clin. Endocrinol. Metab., February 1, 2005; 90(2): 768 - 774.
[Abstract] [Full Text] [PDF]


Home page
J. Clin. Endocrinol. Metab.Home page
S. Blanchette, K. Blouin, C. Richard, P. Dupont, V. Luu-The, and A. Tchernof
Expression and Activity of 20{alpha}-Hydroxysteroid Dehydrogenase (AKR1C1) in Abdominal Subcutaneous and Omental Adipose Tissue in Women
J. Clin. Endocrinol. Metab., January 1, 2005; 90(1): 264 - 270.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
M. E. Hafidi, I. Perez, J. Zamora, V. Soto, G. Carvajal-Sandoval, and G. Banos
Glycine intake decreases plasma free fatty acids, adipose cell size, and blood pressure in sucrose-fed rats
Am J Physiol Regulatory Integrative Comp Physiol, December 1, 2004; 287(6): R1387 - R1393.
[Abstract] [Full Text] [PDF]


Home page
Arterioscler. Thromb. Vasc. Bio.Home page
D.C. Chan, G.F. Watts, P.H.R. Barrett, A.J. Whitfield, and F.M. van Bockxmeer
ATP-Binding Cassette Transporter G8 Gene As a Determinant of Apolipoprotein B-100 Kinetics in Overweight Men
Arterioscler Thromb Vasc Biol, November 1, 2004; 24(11): 2188 - 2191.
[Abstract] [Full Text] [PDF]


Home page
Arch Intern MedHome page
Y. W. Aude, A. S. Agatston, F. Lopez-Jimenez, E. H. Lieberman, Marie Almon, M. Hansen, G. Rojas, G. A. Lamas, and C. H. Hennekens
The National Cholesterol Education Program Diet vs a Diet Lower in Carbohydrates and Higher in Protein and Monounsaturated Fat: A Randomized Trial
Arch Intern Med, October 25, 2004; 164(19): 2141 - 2146.
[Abstract] [Full Text] [PDF]


Home page
J Mol EndocrinolHome page
C Bolduc, M Larose, M Yoshioka, P Ye, P Belleau, C Labrie, J Morissette, V Raymond, F Labrie, and J St-Amand
Effects of dihydrotestosterone on adipose tissue measured by serial analysis of gene expression
J. Mol. Endocrinol., October 1, 2004; 33(2): 429 - 444.
[Abstract] [Full Text] [PDF]


Home page
J. Clin. Endocrinol. Metab.Home page
E. T. Schroeder, L. Zheng, M. D. Ong, C. Martinez, C. Flores, Y. Stewart, C. Azen, and F. R. Sattler
Effects of Androgen Therapy on Adipose Tissue and Metabolism in Older Men
J. Clin. Endocrinol. Metab., October 1, 2004; 89(10): 4863 - 4872.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Clin. Nutr.Home page
C.-J. Tsai, M. F Leitzmann, W. C Willett, and E. L Giovannucci
Prospective study of abdominal adiposity and gallstone disease in US men
Am. J. Clinical Nutrition, July 1, 2004; 80(1): 38 - 44.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Heart Circ. Physiol.Home page
G. E. Alvarez, T. P. Ballard, S. D. Beske, and K. P. Davy
Subcutaneous obesity is not associated with sympathetic neural activation
Am J Physiol Heart Circ Physiol, July 1, 2004; 287(1): H414 - H418.
[Abstract] [Full Text] [PDF]


Home page
ANN INTERN MEDHome page
T. Hayashi, E. J. Boyko, D. L. Leonetti, M. J. McNeely, L. Newell-Morris, S. E. Kahn, and W. Y. Fujimoto
Visceral Adiposity Is an Independent Predictor of Incident Hypertension in Japanese Americans
Ann Intern Med, June 15, 2004; 140(12): 992 - 1000.
[Abstract] [Full Text] [PDF]


Home page
J. Clin. Endocrinol. Metab.Home page
M. C. Carr and J. D. Brunzell
Abdominal Obesity and Dyslipidemia in the Metabolic Syndrome: Importance of Type 2 Diabetes and Familial Combined Hyperlipidemia in Coronary Artery Disease Risk
J. Clin. Endocrinol. Metab., June 1, 2004; 89(6): 2601 - 2607.
[Abstract] [Full Text] [PDF]


Home page
J. Nutr.Home page
H. Wergedahl, B. Liaset, O. A. Gudbrandsen, E. Lied, M. Espe, Z. Muna, S. Mork, and R. K. Berge
Fish Protein Hydrolysate Reduces Plasma Total Cholesterol, Increases the Proportion of HDL Cholesterol, and Lowers Acyl-CoA:Cholesterol Acyltransferase Activity in Liver of Zucker Rats
J. Nutr., June 1, 2004; 134(6): 1320 - 1327.
[Abstract] [Full Text] [PDF]


Home page
Arterioscler. Thromb. Vasc. Bio.Home page
I. Lemieux
Energy Partitioning in Gluteal-Femoral Fat: Does the Metabolic Fate of Triglycerides Affect Coronary Heart Disease Risk?
Arterioscler Thromb Vasc Biol, May 1, 2004; 24(5): 795 - 797.
[Full Text]


Home page
J. Clin. Endocrinol. Metab.Home page
S. Alam, M. Stolinski, C. Pentecost, M. A. Boroujerdi, R. H. Jones, P. H. Sonksen, and A. M. Umpleby
The Effect of a Six-Month Exercise Program on Very Low-Density Lipoprotein Apolipoprotein B Secretion in Type 2 Diabetes
J. Clin. Endocrinol. Metab., February 1, 2004; 89(2): 688 - 694.
[Abstract] [Full Text] [PDF]


Home page
DiabetesHome page
D. Dabelea, G. Kinney, J. K. Snell-Bergeon, J. E. Hokanson, R. H. Eckel, J. Ehrlich, S. Garg, R. F. Hamman, and M. Rewers
Effect of Type 1 Diabetes on the Gender Difference in Coronary Artery Calcification: a Role for Insulin Resistance?: The Coronary Artery Calcification in Type 1 Diabetes (CACTI) Study
Diabetes, November 1, 2003; 52(11): 2833 - 2839.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Clin. Nutr.Home page
S. K Fried and S. P Rao
Sugars, hypertriglyceridemia, and cardiovascular disease
Am. J. Clinical Nutrition, October 1, 2003; 78(4): 873S - 880.
[Abstract] [Full Text] [PDF]


Home page
J. Nutr.Home page
J. M. Dorn, K. Hovey, P. Muti, J. L. Freudenheim, M. Russell, T. H. Nochajski, and M. Trevisan
Alcohol Drinking Patterns Differentially Affect Central Adiposity as Measured by Abdominal Height in Women and Men
J. Nutr., August 1, 2003; 133(8): 2655 - 2662.
[Abstract] [Full Text] [PDF]


Home page
JAMAHome page
J.-L. Chiasson, R. G. Josse, R. Gomis, M. Hanefeld, A. Karasik, and M. Laakso
Acarbose Treatment and the Risk of Cardiovascular Disease and Hypertension in Patients With Impaired Glucose Tolerance: The STOP-NIDDM Trial
JAMA, July 23, 2003; 290(4): 486 - 494.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Endocrinol. Metab.Home page
T.-B. Nguyen-Duy, M. Z. Nichaman, T. S. Church, S. N. Blair, and R. Ross
Visceral fat and liver fat are independent predictors of metabolic risk factors in men
Am J Physiol Endocrinol Metab, June 1, 2003; 284(6): E1065 - E1071.
[Abstract] [Full Text] [PDF]


Home page
Diabetes CareHome page
T. Hayashi, E. J. Boyko, D. L. Leonetti, M. J. McNeely, L. Newell-Morris, S. E. Kahn, and W. Y. Fujimoto
Visceral Adiposity and the Risk of Impaired Glucose Tolerance: A prospective study among Japanese Americans
Diabetes Care, March 1, 2003; 26(3): 650 - 655.
[Abstract] [Full Text] [PDF]


Home page
StrokeHome page
M. De Michele, S. Panico, A. Iannuzzi, E. Celentano, A. V. Ciardullo, R. Galasso, L. Sacchetti, F. Zarrilli, M. G. Bond, and P. Rubba
Association of Obesity and Central Fat Distribution With Carotid Artery Wall Thickening in Middle-Aged Women
Stroke, December 1, 2002; 33(12): 2923 - 2928.
[Abstract] [Full Text] [PDF]


Home page
Arch Intern MedHome page
P. C. Y. Tong, Z. S. K. Lee, M.-M. Sea, C.-C. Chow, G. T. C. Ko, W.-B. Chan, W.-Y. So, R. C. W. Ma, R. Ozaki, J. Woo, et al.
The Effect of Orlistat-Induced Weight Loss, Without Concomitant Hypocaloric Diet, on Cardiovascular Risk Factors and Insulin Sensitivity in Young Obese Chinese Subjects With or Without Type 2 Diabetes
Arch Intern Med, November 25, 2002; 162(21): 2428 - 2435.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Clin. Nutr.Home page
S. Zhu, Z. Wang, S. Heshka, M. Heo, M. S Faith, and S. B Heymsfield
Waist circumference and obesity-associated risk factors among whites in the third National Health and Nutrition Examination Survey: clinical action thresholds
Am. J. Clinical Nutrition, October 1, 2002; 76(4): 743 - 743.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Clin. Nutr.Home page
E. Dewailly, C. Blanchet, S. Gingras, S. Lemieux, and B. J. Holub
Cardiovascular disease risk factors and n-3 fatty acid status in the adult population of James Bay Cree
Am. J. Clinical Nutrition, July 1, 2002; 76(1): 85 - 92.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Clin. Nutr.Home page
J.-M. Oppert, M.-A. Charles, N. Thibult, B. Guy-Grand, E. Eschwege, and P. Ducimetiere
Anthropometric estimates of muscle and fat mass in relation to cardiac and cancer mortality in men: the Paris Prospective Study
Am. J. Clinical Nutrition, June 1, 2002; 75(6): 1107 - 1113.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Clin. Nutr.Home page
I. Janssen, S. B Heymsfield, D. B Allison, D. P Kotler, and R. Ross
Body mass index and waist circumference independently contribute to the prediction of nonabdominal, abdominal subcutaneous, and visceral fat
Am. J. Clinical Nutrition, April 1, 2002; 75(4): 683 - 688.
[Abstract] [Full Text] [PDF]


Home page
J. Clin. Endocrinol. Metab.Home page
P. G. McTernan, L. A. Anderson, A. J. Anwar, M. C. Eggo, J. Crocker, A. H. Barnett, P. M. Stewart, and S. Kumar
Glucocorticoid Regulation of P450 Aromatase Activity in Human Adipose Tissue: Gender and Site Differences
J. Clin. Endocrinol. Metab., March 1, 2002; 87(3): 1327 - 1336.
[Abstract] [Full Text] [PDF]


Home page
DiabetesHome page
A. V. Greco, G. Mingrone, A. Giancaterini, M. Manco, M. Morroni, S. Cinti, M. Granzotto, R. Vettor, S. Camastra, and E. Ferrannini
Insulin Resistance in Morbid Obesity: Reversal With Intramyocellular Fat Depletion
Diabetes, January 1, 2002; 51(1): 144 - 151.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Clin. Nutr.Home page
E. Dewailly, C. Blanchet, S. Gingras, S. Lemieux, L. Sauve, J. Bergeron, and B. J. Holub
Relations between n-3 fatty acid status and cardiovascular disease risk factors among Quebecers
Am. J. Clinical Nutrition, November 1, 2001; 74(5): 603 - 611.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Clin. Nutr.Home page
E. Dewailly, C. Blanchet, S. Lemieux, L. Sauve, S. Gingras, P. Ayotte, and B. J. Holub
n-3 Fatty acids and cardiovascular disease risk factors among the Inuit of Nunavik
Am. J. Clinical Nutrition, October 1, 2001; 74(4): 464 - 473.
[Abstract] [Full Text] [PDF]


Home page
JAMAHome page
D. S. Michaud, E. Giovannucci, W. C. Willett, G. A. Colditz, M. J. Stampfer, and C. S. Fuchs
Physical Activity, Obesity, Height, and the Risk of Pancreatic Cancer
JAMA, August 22, 2001; 286(8): 921 - 929.
[Abstract] [Full Text] [PDF]


Home page
J. Clin. Endocrinol. Metab.Home page
J. L. Clasey, A. Weltman, J. Patrie, J. Y. Weltman, S. Pezzoli, C. Bouchard, M. O. Thorner, and M. L. Hartman
Abdominal Visceral Fat and Fasting Insulin Are Important Predictors of 24-Hour GH Release Independent of Age, Gender, and Other Physiological Factors
J. Clin. Endocrinol. Metab., August 1, 2001; 86(8): 3845 - 3852.
[Abstract] [Full Text] [PDF]


Home page
Diabetes CareHome page
W. F. DeNino, A. Tchernof, I. J. Dionne, M. J. Toth, P. A. Ades, C. K. Sites, and E. T. Poehlman
Contribution of Abdominal Adiposity to Age-Related Differences in Insulin Sensitivity and Plasma Lipids in Healthy Nonobese Women
Diabetes Care, May 1, 2001; 24(5): 925 - 932.
[Abstract] [Full Text]


Home page
BMJHome page
J.-P. Després, I. Lemieux, and D. Prud'homme
Treatment of obesity: need to focus on high risk abdominally obese patients
BMJ, March 24, 2001; 322(7288): 716 - 720.
[Full Text]


Home page
DiabetesHome page
L. Pérusse, T. Rice, Y. C. Chagnon, J.-P. Després, S. Lemieux, S. Roy, M. Lacaille, M.-A. Ho-Kim, M. Chagnon, M. A. Province, et al.
A Genome-Wide Scan for Abdominal Fat Assessed by Computed Tomography in the Quebec Family Study
Diabetes, March 1, 2001; 50(3): 614 - 621.
[Abstract] [Full Text]


Home page
DiabetesHome page
L. W. Castellani, A. M. Goto, and A. J. Lusis
Studies With Apolipoprotein A-II Transgenic Mice Indicate a Role for HDLs in Adiposity and Insulin Resistance
Diabetes, March 1, 2001; 50(3): 643 - 651.
[Abstract] [Full Text]


Home page
Diabetes CareHome page
G. N. Thomas, B. Tomlinson, J. C.N. Chan, J. E. Sanderson, C. S. Cockram, and J. A.J.H. Critchley
Renin-Angiotensin System Gene Polymorphisms, Blood Pressure, Dyslipidemia, and Diabetes in Hong Kong Chinese: A significant association of the ACE insertion/deletion polymorphism with type 2 diabetes
Diabetes Care, February 1, 2001; 24(2): 356 - 361.
[Abstract] [Full Text]


Home page
J. Nutr.Home page
S. E. Kahn, R. L. Prigeon, R. S. Schwartz, W. Y. Fujimoto, R. H. Knopp, J. D. Brunzell, and D. Porte Jr.
Obesity, Body Fat Distribution, Insulin Sensitivity and Islet {{beta}}-Cell Function as Explanations for Metabolic Diversity
J. Nutr., February 1, 2001; 131(2): 354S - 360.
[Abstract] [Full Text]


Home page
J. Appl. Physiol.Home page
N. A. Lynch, B. J. Nicklas, D. M. Berman, K. E. Dennis, and A. P. Goldberg
Reductions in visceral fat during weight loss and walking are associated with improvements in {V}O2 max
J Appl Physiol, January 1, 2001; 90(1): 99 - 104.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Clin. Nutr.Home page
Y. G Casas, B. C Schiller, C. A DeSouza, and D. R Seals
Total and regional body composition across age in healthy Hispanic and white women of similar socioeconomic status
Am. J. Clinical Nutrition, January 1, 2001; 73(1): 13 - 18.
[Abstract] [Full Text] [PDF]


Home page
Endocr. Rev.Home page
B. L. Wajchenberg
Subcutaneous and Visceral Adipose Tissue: Their Relation to the Metabolic Syndrome
Endocr. Rev., December 1, 2000; 21(6): 697 - 738.
[Abstract] [Full Text]


Home page
Am. J. Clin. Nutr.Home page
D. A Schaumberg, R. J Glynn, W. G Christen, S. E Hankinson, and C. H Hennekens
Relations of body fat distribution and height with cataract in men
Am. J. Clinical Nutrition, December 1, 2000; 72(6): 1495 - 1502.
[Abstract] [Full Text] [PDF]


Home page
J. Clin. Pathol.Home page
H Merzouk, M Bouchenak, B Loukidi, S Madani, J Prost, and J Belleville
Fetal macrosomia related to maternal poorly controlled type 1 diabetes strongly impairs serum lipoprotein concentrations and composition
J. Clin. Pathol., December 1, 2000; 53(12): 917 - 923.
[Abstract] [Full Text] [PDF]


Home page
J. Lipid Res.Home page
P. Imbeault, C. Couillard, A. Tremblay, J-P. Després, and P. Mauriège
Reduced {alpha}2-adrenergic sensitivity of subcutaneous abdominal adipocytes as a modulator of fasting and postprandial triglyceride levels in men
J. Lipid Res., September 1, 2000; 41(9): 1367 - 1375.
[Abstract] [Full Text]


Home page
J. Nutr.Home page
M. R. Peluso, T. A. Winters, M. F. Shanahan, and W. J. Banz
A Cooperative Interaction between Soy Protein and Its Isoflavone-Enriched Fraction Lowers Hepatic Lipids in Male Obese Zucker Rats and Reduces Blood Platelet Sensitivity in Male Sprague-Dawley Rats
J. Nutr., September 1, 2000; 130(9): 2333 - 2342.
[Abstract] [Full Text]


Home page
Arterioscler. Thromb. Vasc. Bio.Home page
J.-P. Despres, C. Couillard, J. Gagnon, J. Bergeron, A. S. Leon, D. C. Rao, J. S. Skinner, J. H. Wilmore, and C. Bouchard
Race, Visceral Adipose Tissue, Plasma Lipids, and Lipoprotein Lipase Activity in Men and Women : The Health, Risk Factors, Exercise Training, and Genetics (HERITAGE) Family Study
Arterioscler Thromb Vasc Biol, August 1, 2000; 20(8): 1932 - 1938.
[Abstract] [Full Text] [PDF]


Home page
ANN INTERN MEDHome page
R. Ross, D. Dagnone, P. J.H. Jones, H. Smith, A. Paddags, R. Hudson, and I. Janssen
Reduction in Obesity and Related Comorbid Conditions after Diet-Induced Weight Loss or Exercise-Induced Weight Loss in Men: A Randomized, Controlled Trial
Ann Intern Med, July 18, 2000; 133(2): 92 - 103.
[Abstract] [Full Text] [PDF]


Home page
Int J EpidemiolHome page
J. Sundquist and M. Winkleby
Country of birth, acculturation status and abdominal obesity in a national sample of Mexican-American women and men
Int. J. Epidemiol., June 1, 2000; 29(3): 470 - 477.
[Abstract] [Full Text] [PDF]


Home page
QJMHome page
G.F. WATTS, S. HERRMANN, and F.M. RICHES
Effects of diet and serotonergic agonist on hepatic apolipoprotein B-100 secretion and endothelial function in obese men
QJM, March 1, 2000; 93(3): 153 - 161.
[Abstract] [Full Text] [PDF]


Home page
Arterioscler. Thromb. Vasc. Bio.Home page
M. G. Baroni, M. P. D’Andrea, A. Montali, G. Pannitteri, F. Barilla, F. Campagna, E. Mazzei, S. Lovari, F. Seccareccia, P. P. Campa, et al.
A Common Mutation of the Insulin Receptor Substrate-1 Gene Is A Risk Factor for Coronary Artery Disease
Arterioscler Thromb Vasc Biol, December 1, 1999; 19(12): 2975 - 2980.
[Abstract] [Full Text] [PDF]


Home page
J. Clin. Endocrinol. Metab.Home page
S. Lemieux, G. F. Lewis, A. Ben-Chetrit, G. Steiner, and E. M. Greenblatt
Correction of Hyperandrogenemia by Laparoscopic Ovarian Cautery in Women with Polycystic Ovarian Syndrome Is Not Accompanied by Improved Insulin Sensitivity or Lipid-Lipoprotein Levels
J. Clin. Endocrinol. Metab., November 1, 1999; 84(11): 4278 - 4282.
[Abstract] [Full Text]


Home page
Nephrol Dial TransplantHome page
M. Odamaki, R. Furuya, S. Ohkawa, T. Yoneyama, M. Nishikino, A. Hishida, and H. Kumagai
Altered abdominal fat distribution and its association with the serum lipid profile in non-diabetic haemodialysis patients
Nephrol. Dial. Transplant., October 1, 1999; 14(10): 2427 - 2432.
[Abstract] [Full Text] [PDF]


Home page
J. Clin. Endocrinol. Metab.Home page
F. M. Riches, G. F. Watts, J. Hua, G. R. Stewart, R. P. Naoumova, and P. H. R. Barrett
Reduction in Visceral Adipose Tissue Is Associated with Improvement in Apolipoprotein B-100 Metabolism in Obese Men
J. Clin. Endocrinol. Metab., August 1, 1999; 84(8): 2854 - 2861.
[Abstract] [Full Text]


Home page
JNCI J Natl Cancer InstHome page
R. E. Schoen, C. M. Tangen, L. H. Kuller, G. L. Burke, M. Cushman, R. P. Tracy, A. Dobs, and P. J. Savage
Increased Blood Glucose and Insulin, Body Size, and Incident Colorectal Cancer
J Natl Cancer Inst, July 7, 1999; 91(13): 1147 - 1154.
[Abstract] [Full Text] [PDF]


Home page
J. Am. Coll. Nutr.Home page
R. B. Singh, M. A. Niaz, R. Beegom, G. S Wander, A. S Thakur, and H. S Rissam
Body Fat Percent by Bioelectrical Impedance Analysis and Risk of Coronary Artery Disease Among Urban Men with Low Rates of Obesity: The Indian Paradox
J. Am. Coll. Nutr., June 1, 1999; 18(3): 268 - 273.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Endocrinol. Metab.Home page
J. Saleh, N. Christou, and K. Cianflone
Regional specificity of ASP binding in human adipose tissue
Am J Physiol Endocrinol Metab, May 1, 1999; 276(5): E815 - E821.
[Abstract] [Full Text] [PDF]


Home page
Eur Heart JHome page
A. Rosengren, H. Wedel, and L. Wilhelmsen
Body weight and weight gain during adult life in men in relation to coronary heart disease and mortality: A prospective population study
Eur. Heart J., February 2, 1999; 20(4): 269 - 277.
[Abstract] [PDF]


Home page
Am. J. Clin. Nutr.Home page
D. S Freedman, M. K Serdula, S. R Srinivasan, and G. S Berenson
Relation of circumferences and skinfold thicknesses to lipid and insulin concentrations in children and adolescents: the Bogalusa Heart Study
Am. J. Clinical Nutrition, February 1, 1999; 69(2): 308 - 317.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Endocrinol. Metab.Home page
J. M. H. Elbers, H. Asscheman, J. C. Seidell, and L. J. G. Gooren
Effects of sex steroid hormones on regional fat depots as assessed by magnetic resonance imaging in transsexuals
Am J Physiol Endocrinol Metab, February 1, 1999; 276(2): E317 - E325.
[Abstract] [Full Text] [PDF]